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12-Week Safety and Efficacy Study of BCX4161 as an Oral Prophylaxis Against HAE Attacks — OPuS-2  

Hereditary Angioedema Clinical Trial

Official title:
OPuS-2: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Two Dose Levels of BCX4161 for 12 Weeks as an Oral Prophylaxis Treatment for Attacks of Hereditary Angioedema

Clinical Trial Summary

This study will evaluate the safety and efficacy of an oral treatment, BCX4161, in preventing acute attacks in subjects with hereditary angioedema (HAE). Eligible subjects will be randomized to receive one of two doses of BCX4161 or placebo for 12 weeks. The study will compare the number of acute attacks in each treatment group, as well as a number of other clinical outcomes, and the safety and tolerability of each dose of BCX4161 compared to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02303626
Study type Interventional
Source BioCryst Pharmaceuticals
Contact
Status Completed
Phase Phase 2/Phase 3
Start date November 2014
Completion date January 2016
View Details
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