Clinical Trials Logo

Clinical Trial Summary

It has been known for many years that the heart and the liver are intimately related. There is a mutual interaction between the function of the heart and the liver and a broad spectrum of acute and chronic entities that affect both the heart and the liver. Chronic hepatitis C virus infection affects more than 3% (170 million) of the world's population.


Clinical Trial Description

Assessment of systolic function by echocardiography will be done to 100 hepatitis C virus infected patients who receive antiviral treatment (sofosbuvir and daclatasvir) by biplane simpson's method and by speckle tracking.

Assessment of diastolic function by echocardiography to 30 hepatitis C virus infected patients who will not receive antiviral treatment, by left atrium volume , mitral inflow pattern , tissue doppler annular early and late diastolic velocities . ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03166943
Study type Interventional
Source Assiut University
Contact Yehia Kishk, MD
Phone 00201011030011
Email ytkishk2002@yahoo.com
Status Recruiting
Phase N/A
Start date May 10, 2017
Completion date December 2020

See also
  Status Clinical Trial Phase
Recruiting NCT05738681 - Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial Phase 2/Phase 3
Recruiting NCT05989958 - The Safety and Tolerability Study of HepaCure in Chinese Subjects With Acute-On-Chronic Liver Failure Phase 1
Not yet recruiting NCT06395129 - Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries
Terminated NCT01443923 - Boceprevir Drug Combination for Hepatitis C Treatment in People With and Without HIV Phase 4
Completed NCT00679692 - Evaluation the Growth Factors(IGF-1,IGFBP-3and HGH)in Patients With Chronic Liver Disease N/A
Completed NCT00300209 - Manhattan HIV/Hepatology Brain Bank N/A
Recruiting NCT05563961 - A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers N/A
Recruiting NCT05635266 - Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Completed NCT00160407 - Orlistat (Xenical) in the Treatment of Overweight Patients With Nonalcoholic Steatohepatitis (NASH) Phase 4
Recruiting NCT03692897 - An Observational Study of Patients With Chronic Hepatitis B (CHB) Infection
Completed NCT03509688 - The Curative Effect of Entecavir Combined Resveratrol on HBV patients-a Multi-center, Random, Open Clinical Trial N/A
Recruiting NCT02275195 - Immune Cell Dysfunction in Severe Alcoholic Hepatitis
Completed NCT01740089 - Algeron (Cepeginterferon Alfa-2b) Compared With PegIntron (Peginterferon Alfa-2b) for Treatment of Chronic Hepatitis C Phase 2/Phase 3
Completed NCT00987337 - Filibuvir In Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Subjects Phase 2
Completed NCT00929786 - Anti-tuberculosis (TB) Drug Levels and Hepatotoxicity N/A
Completed NCT00564642 - Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity N/A
Completed NCT00080236 - Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation Phase 2
Recruiting NCT05719480 - A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Liver Cancer
Suspended NCT04306939 - Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
Completed NCT03482388 - Crowdsourcing to Promote HBV and HCV Testing in China N/A