Hepatitis Clinical Trial
Official title:
Epidemiologic Surveillance to Assess Trends in Acute Hepatitis A Among Children in Panama
The purpose of this study is to collect epidemiological and clinical data to assess the vaccine impact and occurrence of confirmed acute hepatitis A cases in sentinel hospitals after the introduction of Havrix™ into the Expanded Program of Immunization.
This is an observational, prospective, multi-centre, sentinel based study in 3 hospitals in
Panama. Hospitals are selected based on population density or hepatitis A disease burden.
The Pan American Health Organization (PAHO) definition for a possible case of acute
hepatitis A are used for subjects aged between >1 month and <15 years.
Data regarding clinical and epidemiologic information are collected and serum samples are
collected to test hepatitis A markers and determine if infection with hepatitis A virus has
recently occurred.
Surveillance will be for a period of approximately 2.5 years from the date of study
initiation.
;
Observational Model: Case-Only, Time Perspective: Prospective
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