Hepatitis E Clinical Trial
Official title:
A Phase Ib Single Center, Randomized, Blinding, Parallel-controlled Clinical Trial to Evaluate the Safety and Immunogenicity of a Recombinant Hepatitis E Vaccine in Healthy Adults Aged 16 to 65 Years Old in China
Hepatitis E is characteristic by sporadic and local epidemic around the world, and mainly
infects adults aged 15 to 40 years old, resulting in the infection rate ranged from 1% to
15%. The investigational hepatitis E vaccine is a recombinant aluminium-adjuvant hepatitis E
vaccine.
This is a single center, randomized, blinding, parallel-controlled phase Ib clinical trial.
This study will determine the safety and immunogenicity of the investigational recombinant
hepatitis E vaccine in healthy adults between 16 and 65 years.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03365921 -
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial)
|
Phase 4 | |
Completed |
NCT02584543 -
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine)
|
Phase 4 | |
Not yet recruiting |
NCT03488589 -
HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for Liver
|
||
Completed |
NCT03601221 -
Seroprevalence Hepatitis E Infection in Healthy Blood Donors
|
||
Completed |
NCT03168412 -
A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule)
|
Phase 4 | |
Completed |
NCT02189603 -
Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®)
|
Phase 4 | |
Completed |
NCT02847507 -
Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb)
|
||
Completed |
NCT02190253 -
Seroprevalence of Hepatitis E in People With an Organ Transplant
|
||
Recruiting |
NCT06457438 -
Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors
|
N/A | |
Completed |
NCT04670419 -
Morbidity and Mortality of Hepatitis E Virus Infections in Belgium
|
||
Completed |
NCT03282474 -
HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE)
|
Phase 2 | |
Terminated |
NCT02558114 -
Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection.
|
Phase 4 | |
Recruiting |
NCT06137313 -
Exposure to Hepatitis E Virus in Occitania, France
|
||
Completed |
NCT02964910 -
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )
|
Phase 4 | |
Completed |
NCT01014845 -
Clinical Trial of Recombinant Hepatitis E Vaccine
|
Phase 3 | |
Recruiting |
NCT05976594 -
Long-term Effectiveness of a Recombinant Hepatitis E Vaccine
|
||
Completed |
NCT02417597 -
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)
|
Phase 4 | |
Completed |
NCT03827395 -
Safety Study of Hepatitis E Vaccine (HEV239)
|
Phase 1 |