Clinical Trials Logo

Clinical Trial Summary

Hepatitis E is characteristic by sporadic and local epidemic around the world, and mainly infects adults aged 15 to 40 years old, resulting in the infection rate ranged from 1% to 15%. The investigational hepatitis E vaccine is a recombinant aluminium-adjuvant hepatitis E vaccine.

This is a single center, randomized, blinding, parallel-controlled phase Ib clinical trial. This study will determine the safety and immunogenicity of the investigational recombinant hepatitis E vaccine in healthy adults between 16 and 65 years.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT02603055
Study type Interventional
Source Jiangsu Province Centers for Disease Control and Prevention
Contact
Status Completed
Phase Phase 1
Start date July 2015
Completion date August 2016

See also
  Status Clinical Trial Phase
Completed NCT03365921 - A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Phase 4
Completed NCT02584543 - A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine) Phase 4
Not yet recruiting NCT03488589 - HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for Liver
Completed NCT03601221 - Seroprevalence Hepatitis E Infection in Healthy Blood Donors
Completed NCT03168412 - A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule) Phase 4
Completed NCT02189603 - Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®) Phase 4
Completed NCT02847507 - Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb)
Completed NCT02190253 - Seroprevalence of Hepatitis E in People With an Organ Transplant
Recruiting NCT06457438 - Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors N/A
Completed NCT04670419 - Morbidity and Mortality of Hepatitis E Virus Infections in Belgium
Completed NCT03282474 - HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE) Phase 2
Terminated NCT02558114 - Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection. Phase 4
Recruiting NCT06137313 - Exposure to Hepatitis E Virus in Occitania, France
Completed NCT02964910 - A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients ) Phase 4
Completed NCT01014845 - Clinical Trial of Recombinant Hepatitis E Vaccine Phase 3
Recruiting NCT05976594 - Long-term Effectiveness of a Recombinant Hepatitis E Vaccine
Completed NCT02417597 - A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli) Phase 4
Completed NCT03827395 - Safety Study of Hepatitis E Vaccine (HEV239) Phase 1