Hepatitis D Clinical Trial
Official title:
DELTA DESCRIBE: the French Collaborative Project
Our global objective is to draw up a photograph of HDV patients over one year in metropolitan France and identify the barriers of screening and care. The investigator suspects a mismatch between HBV and HDV screening, the first step for specialized care pathway in metropolitan France.
Hepatitis Delta virus (HDV) infection is a significant public health disease causing up to 18% of cirrhosis and 20% of hepatocellular carcinoma (HCC) and new therapeutic options are now available. In France, very few epidemiological studies, mainly focused on specific pre-selected hospital populations, are available. There is a crucial need for data in terms of Delta knowledge, suitability of screening, type of prescribers and treatment access. The investigator proposes a retrospective study in order to describe the number of HDV tests (anti-HDV and HDV RNA) performed in metropolitan France and compare it to the potentially expected one, estimated from the number of HBV screening tests performed in one year, from 2016 to 2020. The investigator will also evaluate the number of HCV and HIV screening tests prescribed over the same period and the HDV PCR techniques used. This study will be based on one hand on data from the French Health insurance (first step) and on the other hand on data from private and hospital laboratories (second step). The second step will allow to identify the prescriber of the Delta tests and the HDV positive patients and precise their profile and their medical care. After an initial analysis of the results, The investigator will propose solutions to the barriers encountered and adapted to the identified targets. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02044055 -
Mother-to-child Hepatitis D Transmission
|
N/A | |
| Completed |
NCT02375906 -
The Hepatitis Delta International Network
|
||
| Not yet recruiting |
NCT05394623 -
Prevalence and Burden of Hepatitis D Virus Infection in China Through Preoperative Examination Test (Predict Study)
|
||
| Recruiting |
NCT04863703 -
Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)
|
||
| Recruiting |
NCT06397859 -
Effectiveness and Clinical Outcomes of Long-term Bulevirtide Monotherapy in Patients With HDV-related Compensated Cirrhosis
|
||
| Recruiting |
NCT00001971 -
Evaluation of Patients With Liver Disease
|
||
| Recruiting |
NCT06264583 -
HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV Coinfection
|
||
| Recruiting |
NCT05928000 -
HEllenic Multicenter ReAl-life CLInical Study for Bulevirtide Therapy in Chronic Hepatitis D: HERACLIS-BLV
|
||
| Recruiting |
NCT06122285 -
Effectiveness and Safety of Bulevirtide (BLV) Therapy in Patients With Chronic Hepatitis Delta (CHD) in Italy (D-SHIELD)
|
||
| Terminated |
NCT04847440 -
A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus Coinfection
|
Phase 2 | |
| Completed |
NCT00932971 -
HIDIT II - PegIFN-alfa2a Plus Tenofovir in Chronic Delta Hepatitis
|
Phase 2 | |
| Completed |
NCT06360484 -
Prevalence and Clinical Characterization of Hepatitis D Virus (HDV) Infection Among Sudanese Patients With Hepatitis B Virus
|
||
| Completed |
NCT02511431 -
Treatment of Chronic Delta Hepatitis With Lonafarnib and Ritonavir
|
Phase 2 | |
| Not yet recruiting |
NCT05451082 -
Registry-based Study in Patients With Hepatitis D Virus (HDV) Infection in China
|
||
| Recruiting |
NCT05903742 -
Standardising Care for Hepatitis Delta in the Netherlands
|
||
| Not yet recruiting |
NCT03362866 -
Epidemiology of Hepatitis B, C and Delta in Reunion Island
|
||
| Terminated |
NCT01316185 -
Proof-of-concept Study Evaluating the Safety and Efficacy of EBP921 in Delta Hepatitis (HDV)
|
Phase 1 | |
| Recruiting |
NCT05264272 -
Disease Loads and Status of Treatment
|
||
| Completed |
NCT05002907 -
Epidemiology of Hepatitis B, C and D and HIV Along the Maroni River Bordering French Guiana and Suriname (MaHeVi)
|
||
| Not yet recruiting |
NCT05467553 -
A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection
|
Phase 2 |