Hepatitis C Clinical Trial
Official title:
The Effect of Direct Antiviral Therapy on Hepatitis c Virus-related Thrombocytopenia
| Verified date | December 2017 |
| Source | Assiut University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Autoimmune thrombocytopenic purpura is an immunological disorder characterized by increased platelet destruction due to presence of anti-platelet antibodies. Hepatitis C virus infection, which is one of the most common chronic viral infections worldwide, may cause secondary chronic immune thrombocytopenic purpura. It seemed to play a pathogenic role in autoimmune thrombocytopenic purpura. Moreover, the successful response (negative hepatitis C virus - ribonucleic acid) to tapered steroids and antiviral therapy was useful to revert thrombocytopenia
| Status | Recruiting |
| Enrollment | 50 |
| Est. completion date | September 2019 |
| Est. primary completion date | June 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | N/A and older |
| Eligibility |
Inclusion Criteria: - Hepatitis C virus infection and thrombocytopenia before treatment Exclusion Criteria: - Infection Hepatitis B virus - Hypersplenism - Diseases affecting Bone marrow - Major clotting factors abnormalities eg. Disseminated intravascular coagulopathy, severe Prothrombin deficiency |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Assiut University | Assiut |
| Lead Sponsor | Collaborator |
|---|---|
| Assiut University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | the mean difference on the platelet count | 6 month |
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