Fecal Transplant for Hepatic Encephalopathy

Status Completed

Clinical Trial Summary

The purpose of the study is to determine if fecal microbiota transplant (FMT) can reverse hepatic encephalopathy (HE) in cirrhotic patients who continue to have breakthrough episodes of HE despite maintenance therapy with lactulose and/or rifaximin or metronidazole.

Clinical Trial Description

Subjects receive FMT from a single donor by colonoscopy at week 0 and by enema at weeks 1-4. HE is measured by Inhibitory Control Test (ICT) and Stroop test as well as fasting serum ammonia levels. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03439982
Study type	Interventional
Source	University of Alberta
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	April 12, 2016
Completion date	March 18, 2021

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See also
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