Clinical Trials Logo

Clinical Trial Summary

IgA vasculitis is relatively common in children,especially in Asian countries. Abdominal manifestation could be severe, including bleeding, pancreatitis,appendicitis and intestinal intussusception. Delayed diagnosis could be fatal and cause severe complications.Nowadays no guidelines for those with severe abdominal manifestations in China.However, the most used treatment is steroid. For those severe forms are methylprednisolone pulse, IVIG, immunosuppressants and blood purification. Given the fact that different strategies lead to different endings which varies in cost, adverse effect and clinical outcomes in different medical centers, it is necessary to give birth to a useful and feasible strategy. This clinical trial is a muti-center, randomized,controlled prospective study.Patients with gastrointestinal disease will be recruited in three children's medical centres in Shanghai and will be randomized to two groups: MP group and IVIG group. Cost effect and clinical outcomes will be evaluated. Blood purification will be evaluated as a remedy when MP and IVIG fail to cure.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03647852
Study type Interventional
Source Children's Hospital of Fudan University
Contact Li Sun, MD
Phone +8618017590930
Email lillysun@263.com
Status Recruiting
Phase N/A
Start date September 1, 2019
Completion date October 30, 2025

See also
  Status Clinical Trial Phase
Recruiting NCT05951517 - Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura N/A
Recruiting NCT02939573 - A Randomized Multicenter Study for Isolated Skin Vasculitis Phase 2