Hemostatic Disorder Clinical Trial
Official title:
Hemostatic Disorders Impact on Intensive Care Patients.
1. To assess the incidence of hemostatic disorders among ICU patients.
2. To establish a relationship between supportive treatment and survival in patients with
coagulopathy in ICU.
3. To provide solutions that can help in reduction of the incidence of hemostatic disorders
in ICU patients.
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | September 2020 |
Est. primary completion date | September 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 90 Years |
Eligibility |
Inclusion Criteria: - Intensive care unit patients,aged more than 18 years . - Any Acquired bleeding disorders (platelet disorders; thrombocytopenia, acquired thrombocythemia and thrombocytosis, acquired coagulation defect, Thrombophilia ) Diagnosed in Critical care unit in Assiut university in one year time frame Exclusion Criteria: - Patient less than 18 years. - Patients with Inherited platelet defects ( Amegakaryoctye aplasia and Bernard Soulir syndrome) - Patients with Inherited coagulation defects (e.g.hemophilia , Von Willebrand disease and any inherited coagulation defect. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Hunt BJ. Bleeding and coagulopathies in critical care. N Engl J Med. 2014 Feb 27;370(9):847-59. doi: 10.1056/NEJMra1208626. Review. — View Citation
Retter A, Barrett NA. The management of abnormal haemostasis in the ICU. Anaesthesia. 2015 Jan;70 Suppl 1:121-7, e40-1. doi: 10.1111/anae.12908. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Describe the Pattern of Homeostasis Disorders occur in Critical Care Unit in Assiut University | Study the causes of either bleeding or thrombotic events in Critical care unit. Describe the pattern of the disease regarding age, sex and predisposing factors. | Baseline | |
Secondary | Correlate Supportive and Definitive Treatment and Outcomes of Patients with Homeostasis Disorder in ICU. | Study the forms of transfusion ( e.g.packed red blood cells, Platelet , Fresh frozen plasma), anti bleeding measures (e.g. Tranexamic acid), anticoagulant and anti platelet drugs received by the patients and their outcomes | Baseline |
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