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Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine

Hemorrhoids Clinical Trial

Clinical Trial Summary

24 patients randomly divided into two groups, one of the groups receiving atropine in addition to the planned anaesthesia. Skin conductance parameters to be compared between the two groups.

Clinical Trial Description

Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine.

Study hypothesis: SC is not influenced by i.v. administration of atropine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00328900
Study type Interventional
Source Rikshospitalet University Hospital
Contact Hanne Storm, PhD
Phone +47 23074398
Email hanne.storm@medisin.uio.no
Status Unknown status
Phase N/A
Start date January 2006
View Details
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