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NCT03536195 Clinical Trial

Impact of Renal Replacement Therapy on Coagulation Profile of Patients With Acute Renal Failure

Hemorrhage Clinical Trial

— HEMOSTIR  

Official title:
Impact of Renal Replacement Therapy on Coagulation Profile in Patients With Acute Renal Failure

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03536195
Other study ID # HEMOSTIR (29BRC17.0132)
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 20, 2018
Est. completion date November 23, 2021

Study information
Verified date December 2023
Source University Hospital, Brest
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Renal failure and high plasmatic level of urea have been associated with an increased risk of hemorrhage in surgical patients. There is only sparse data on the impact of renal replacement therapy on homeostatic parameters. The aim of this study is to describe potential changes in homeostatic parameters before and after renal replacement therapy.

Recruitment information / eligibility
Status Completed
Enrollment 14
Est. completion date November 23, 2021
Est. primary completion date November 23, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - critically ill patients - acute renal failure - renal replacement therapy - plasmatic urea > 20 Exclusion Criteria: - chronic renal failure - platelet count less than 80 Giga - V factor less than 70%

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France CHRU de Brest Brest

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary visco elastometry ROTEM (Rotational Thromboelastometry) Change in ROTEM parameters from baseline to after renal replacement therapy
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