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Clinical Trial Summary

Study WP44714 is a Phase I/II, open-label, non-randomized, global, multicenter, multiple-ascending dose (MAD) study in adult and adolescent male participants with severe or moderate hemophilia A with or without factor VIII (FVIII) inhibitors. The aim is to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of multiple ascending doses of NXT007.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05987449
Study type Interventional
Source Hoffmann-La Roche
Contact Reference Study ID Number: WP44714 https://forpatients.roche.com
Phone 888-662-6728 (U.S. Only)
Email global-roche-genentech-trials@gene.com
Status Recruiting
Phase Phase 1/Phase 2
Start date September 21, 2023
Completion date June 16, 2032

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