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2-cohort Study of Adult Patients With Severe Hemophilia A in Greece — HAMLET  

Hemophilia A Clinical Trial

Official title:
Prospective, Observational, 2-cohort Study of Adult Patients With Severe Hemophilia A in Greece. Cost,Clinical Outcomes and Quality of Life Comparison Between on Demand and Secondary Prophylaxis Treatment Strategies

Clinical Trial Summary

This study is a prospective, single center, observational, 2-cohort study of adult patients with severe Hemophilia A. There is no randomization procedure and all patients will be treated as per usual clinical practice. Patients will be followed up for 18 months after enrolment.

Clinical Trial Description

The primary therapy for hemophilia is coagulation factor replacement, given either episodically on demand (OD) for the treatment of acute bleeds or prophylactically to prevent them.

The last years there has been an interest to study the comparative effectiveness of OD vs. SP (Secondary Prophylaxis) treatment strategies so as to create an evidence based platform to guide both clinical decision making and quantify the economic aspects of each treatment alternative. In Greece relevant information is lacking, thus it is imperative to study how patients on different treatment strategies are managed in a real-life setting in Greece, including the main factors associated with increased health care utilization, clinical success and patient well being. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02319070
Study type Observational
Source Bayer
Contact
Status Completed
Phase
Start date January 13, 2015
Completion date February 28, 2018
View Details
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