Cardiorespiratory Effects of Nasal High Frequency Ventilation in Neonates

Status Completed

Clinical Trial Summary

The aim of the present work is to study the cardio-respiratory effects of non-invasive ventilation (nasal high-frequency ventilation and nasal CPAP) as an initial therapy of respiratory distress in moderate and late preterm infants as regard: I. Primary outcomes: - Duration of the non- invasive respiratory support. - Need of invasive ventilation in the first 72 hours. - Short-term complications such as air leak syndromes, pulmonary hemorrhage, intraventricular hemorrhage, and nasal trauma. II. Secondary outcomes: - Need for surfactant administration. - Days on invasive mechanical ventilation. - Days on supplemental oxygen. - Duration of hospital stay. - Mortality rate. III. Hemodynamic changes during the period of non-invasive ventilation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05706428
Study type	Interventional
Source	Alexandria University
Contact
Status	Completed
Phase	N/A
Start date	February 1, 2023
Completion date	October 13, 2023

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