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Late Effects and HRQoL in Survivors of Allo-HSCT - a Cross Sectional Study

Hematological Diseases Clinical Trial

Official title:
Late Effects and Health-Related Quality of Life in Survivors of Allogeneic Hematopoietic - a Cross-sectional Study

Clinical Trial Summary

The cross-sectional study aims to describe the burden of late effects and survivorship-specific health-related quality of life in a nationwide cohort of patients treated with allo-HSCT in Denmark. Further, identify demographic, medical or personal factors associated with better self-reported health and quality of life.

Clinical Trial Description

Objective The cross-sectional study aims to describe the burden of late effects and survivorship-specific health-related quality of life in a nationwide cohort of patients treated with allo-HSCT in Denmark. Further, identify demographic, medical or personal factors associated with better self-reported health and quality of life. Method An observational, descriptive, cross-sectional study using clinical data and self-reported questionnaires to assess the occurrence of comorbidities and self-reported late effects in survivors treated with allo-HSCT in Denmark between 1970 and 2024. Study population All survivors treated for malignant or non-malignant hematological disease with allo-HCST at the age of 18-79 years from 1970-2024 in Denmark are eligible (n=1.436). Endpoints - Self-reported survivorship specific HRQoL measured by EORTC-QOL- Survivorship 100. - Degree of health literacy measured by the Health Literacy Questionnaire (HLQ). - Occurrence or degree of Chronic Graft Versus Host Disease measured by modified Lee Chronic Graft versus host disease Symptom Scale. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06277479
Study type Observational
Source Rigshospitalet, Denmark
Contact
Status Enrolling by invitation
Phase
Start date March 2024
Completion date September 2024
View Details
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