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Clinical Trial Summary

The purpose of the study is to determine if pulse steroids are more efficacious and safer than the standard treatment with oral corticosteroids.


Clinical Trial Description

Currently there is no prospective study in hemangioma patients answering critical questions such as: which type of steroid should be used,how much should we use and for how long. This study is an investigator blinded study with two arms:one arm is receiving standard treatment with daily oral corticosteroids and the other is receiving intravenous pulse corticosteroids daily for 3 days, monthly for 3 months. The main outcome of the study is assess the efficacy of each treament modality as the percentage improvement in the hemangioma's appearance. The secondary outcomes are the safety profiles of the two drugs and the changes in the angiogenesis markers as a result of treatment intervention. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00312520
Study type Interventional
Source The Hospital for Sick Children
Contact
Status Completed
Phase Phase 3
Start date July 2002
Completion date June 2005

See also
  Status Clinical Trial Phase
Completed NCT00576888 - Registry for Vascular Anomalies Associated With Coagulopathy
Completed NCT00577213 - Diagnosis of Hemangiomas and Vascular Malformations N/A
Completed NCT00866827 - Airway Vascular Lesions