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Clinical Trial Summary

To explore the effect of intraoperative sodium creatine phosphate on myocardial protection in patients undergoing valve surgery


Clinical Trial Description

Objective: To explore the effect of intraoperative sodium creatine phosphate on myocardial protection in patients undergoing valve surgery Methods: 250 patients undergoing valve surgery were randomly divided into experimental group and control group. 5g creatine phosphate was dissolved in 50ml saline solution. After induction of anesthesia, the patients were first given a load dose of 1g, 20min (30ml / h) , And then pumped at a rate of 1 g / h (10 ml / h). The control group was treated with saline in the same manner. The cTnI level was measured at the corresponding time points. Hemodynamic indexes and postoperative complications were recorded. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03186053
Study type Interventional
Source Chinese Academy of Medical Sciences, Fuwai Hospital
Contact Guyan WANG, M.D.
Phone +86-13910985139
Email 13910985139@163.com
Status Recruiting
Phase N/A
Start date June 15, 2017
Completion date December 31, 2018

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