Genetic Predictors of Renal Dysfunction Following Heart Transplantation

Status Active, not recruiting

Clinical Trial Summary

Kidney disease is a common problem after heart transplantation. It may be caused by anti-rejection medications such as cyclosporine or tacrolimus. However, the reason why some people develop kidney problems after a heart transplant, but other people do not, is not fully known. This study plans to learn more about the relationship between a person's genetic make-up (DNA; deoxyribonucleic acid) and the risk of kidney problems after a heart transplant. The long-term goal of this research is to identify genetic variations that may help predict the development of kidney problems after heart transplantation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01686191
Study type	Observational
Source	University of Colorado, Denver
Contact
Status	Active, not recruiting
Phase
Start date	August 2012
Completion date	December 2025

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See also
Status	Clinical Trial	Phase
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Completed	`NCT01028599` - Effect of Physical Training on Oxygen Uptake and Endothelial Function in Heart Transplant Recipients	N/A
Completed	`NCT00531921` - Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival	N/A
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Withdrawn	`NCT00780377` - Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients	N/A
Withdrawn	`NCT00780637` - Brachial Artery t-PA Release in Heart Transplant Recipients	N/A
Terminated	`NCT00121784` - Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients	Phase 4
Withdrawn	`NCT00572286` - Non-invasive Evaluation of Heart Transplant Rejection- Pilot Study	N/A
Completed	`NCT00123331` - Rapamycin Use in Calcineurin Inhibitor (CNI)-Free Immunosuppression for Stabilization/Improvement of Renal Function After Heart Transplantation	Phase 4