Clinical Trials Logo
  1. Home
  2. Heart Transplant Rejection
  3. NCT05205551

Prospera Test Evaluation in Cardiac Transplant (ProTECT) — ProTECT  

Heart Transplant Rejection Clinical Trial

Official title:
Prospera Test Evaluation in Cardiac Transplant (ProTECT)

Clinical Trial Summary

The ProTECT registry is an observational longitudinal, multi-center study observing patients undergoing heart transplant for whom Prospera testing is part of routine clinical care, who are enrolled within 60 days of heart transplantation.

Clinical Trial Description

The ProTECT registry is an observational longitudinal, multi-center study observing patients undergoing heart transplant for whom Prospera™ testing is part of routine clinical care, who are enrolled within 60 days of heart transplantation. Patients who are enrolled in this study should have blood drawn for Prospera™ testing at regular intervals per routine clinical care. Prospera™ test results and results of surveillance endomyocardial biopsies, laboratory testing, echocardiograms, angiography and hemodynamic monitoring performed to monitor cardiac status and for signs of transplant rejection, as well as medications and post-transplant re-vascularization and surgical procedures will be recorded in the electronic case report form (eCRF). Patient management decisions, even those informed by the Prospera™ test result, are made based on the individual judgment of the healthcare providers participating in the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05205551
Study type Observational [Patient Registry]
Source Natera, Inc.
Contact
Status Active, not recruiting
Phase
Start date October 1, 2021
Completion date June 30, 2027
View Details
See also
  Status Clinical Trial Phase
Completed NCT06436027 - Molecular Diagnosis of Heart Allograft Rejection Using Intra-Graft Targeted Gene Expression Profiling.
Not yet recruiting NCT05732779 - Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients N/A
Active, not recruiting NCT05064462 - TTV Viral Load in Heart Transplant Recipients
Recruiting NCT04973943 - Donor-derived Cell Free DNA as a New Biomarker in Cardiac Acute Rejection
Completed NCT03477383 - A New Biomarker for the Non-invasive Diagnosis of Rejection After Heart Transplantation
Not yet recruiting NCT05772442 - Cardiac Transplant Metabolomics With and Without Rejection
Recruiting NCT04707872 - Trifecta-Heart cfDNA-MMDx Study
Recruiting NCT06064123 - Biomarkers for Diagnosis, Prognosis, and Targeted Therapy After Heart Transplantation
Active, not recruiting NCT04921774 - Research on Patients With Heart Transplantation
Recruiting NCT04226521 - Extracorporeal Photopheresis and Early Cardiac Graft Vasculopathy N/A
Completed NCT03393793 - HEart trAnsplantation Registry of piTie-Salpetriere University Hospital
Completed NCT01136135 - Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Cardiac Transplant Rejection N/A
Completed NCT03833050 - The TOGETHER Project - Heart
Active, not recruiting NCT03373227 - Phase II Study Evaluating the Efficacy of Tacrolimus Extended Release Tablets to Twice Daily Tacrolimus Dosing Regimen Phase 2
Active, not recruiting NCT03695601 - Surveillance HeartCare® Outcomes Registry
Active, not recruiting NCT01397812 - Heartsbreath Test for Heart Transplant Rejection N/A
Active, not recruiting NCT05184426 - MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT)