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Clinical Trial Summary

High-intensity training (HIT) has repeatedly been documented to have superior positive effects compared to moderate exercise in patients with coronary heart disease and heart failure. Since heart transplant recipients (HTx), have a denervated heart with different respond to exercise, HIT has previously not been introduced among these patients. Rikshospitalet carried out a RCT to investigate this (the TEX study 2009-2012), and found that this form of exercise also was highly effective and safe in long term HTx with clinically significant improvement in VO2peak, muscular exercise capasity, general HRQoL, and even slower progression of CAV (coronary allograft vasculopathy). Based on these findings we ask the following questions in this follow-up study:

1. Would the effect on VO2peak, HRQoL,muscle capacity and CAV obtained during the study period continue during long term follow up (5 years)?

2. Is the intervention group more physical active after HIT compared to the control group?


Clinical Trial Description

n/a


Study Design

Observational Model: Case-Crossover, Time Perspective: Cross-Sectional


Related Conditions & MeSH terms


NCT number NCT02213770
Study type Observational
Source Oslo University Hospital
Contact
Status Completed
Phase N/A
Start date August 2014
Completion date November 2015

See also
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Active, not recruiting NCT01759966 - Autonomic Cardiovascular Control After Heart Transplantation
Completed NCT01914406 - High-intensity Interval Training Versus Moderate Continuous Training in Heart Transplant Recipients. N/A
Completed NCT01796379 - High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia N/A
Completed NCT03662789 - Intravenous Iron Supplement for Iron Deficiency in Cardiac Transplant Recipients Phase 2/Phase 3