Long Term Effect of High-intensity Training After Heart Transplantation

Status Completed

Clinical Trial Summary

High-intensity training (HIT) has repeatedly been documented to have superior positive effects compared to moderate exercise in patients with coronary heart disease and heart failure. Since heart transplant recipients (HTx), have a denervated heart with different respond to exercise, HIT has previously not been introduced among these patients. Rikshospitalet carried out a RCT to investigate this (the TEX study 2009-2012), and found that this form of exercise also was highly effective and safe in long term HTx with clinically significant improvement in VO2peak, muscular exercise capasity, general HRQoL, and even slower progression of CAV (coronary allograft vasculopathy). Based on these findings we ask the following questions in this follow-up study:

1. Would the effect on VO2peak, HRQoL,muscle capacity and CAV obtained during the study period continue during long term follow up (5 years)?

2. Is the intervention group more physical active after HIT compared to the control group?

Clinical Trial Description

n/a

Study Design

Observational Model: Case-Crossover, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Heart Transplant Recipients

Clinical Trial Details

NCT number	NCT02213770
Study type	Observational
Source	Oslo University Hospital
Contact
Status	Completed
Phase	N/A
Start date	August 2014
Completion date	November 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02077764` - The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.	N/A
Terminated	`NCT01278745` - Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation	Phase 2
Recruiting	`NCT06190171` - Respiratory Strength Training in Heart Transplant Recipients	N/A
Completed	`NCT01912248` - Acute Effect of Strength Training on Blood Pressure in Cardiac Patients	N/A
Active, not recruiting	`NCT01759966` - Autonomic Cardiovascular Control After Heart Transplantation
Completed	`NCT01914406` - High-intensity Interval Training Versus Moderate Continuous Training in Heart Transplant Recipients.	N/A
Completed	`NCT01796379` - High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia	N/A
Completed	`NCT03662789` - Intravenous Iron Supplement for Iron Deficiency in Cardiac Transplant Recipients	Phase 2/Phase 3