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Heart Septal Defects clinical trials

View clinical trials related to Heart Septal Defects.

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NCT ID: NCT02957201 Completed - Clinical trials for Atrial Septal Defect

The Effect on EPCs by Successful Cardiac Occlusion Device Implantation

EPIC
Start date: July 2016
Phase: N/A
Study type: Interventional

All patients awaiting to have either a left atrial appendage closure (LAA) or patent foramen ovale (PFO) or Atrial Septal Defect (ASD) closure device as part of standard care will be identified and reviewed in cardiology clinics. These patients will be placed on waiting list to undergo the procedure. Patient-participants will be consented on the date of admission for device closure implantation. The study will recruit 20 patients divided into; 10 patients undergoing PFO/ASD closure and 10 patients undergoing LAA closure. EPC will be measured on the day of the device implantation, day 0 and prior to discharge on day 1. Patient participants are admitted overnight after the device closure implantation. Then on subsequent out patient cardiology research clinic follow appointments on days (3-4) and (7-8).

NCT ID: NCT02914652 Completed - Clinical trials for Ventricular Septal Defect

The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.

Start date: October 15, 2016
Phase: Phase 4
Study type: Interventional

The overall objective for this study is to test whether β2-agonists will affect the cardiopulmonary capacity of VSD-operated patients compared with un-operated VSD-patients and healthy age- and gender-matched controls.

NCT ID: NCT02867930 Completed - Heart Valve Disease Clinical Trials

Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography

KDTEE
Start date: June 2016
Phase: Phase 4
Study type: Interventional

The purpose of the study is to compare dexmedetomidine and ketofol to find a suitable alternative for moderate sedation in out-patient diagnostic trans-esophageal echocardiography.

NCT ID: NCT02861963 Completed - Clinical trials for Pulmonary Atresia With Ventricular Septal Defect

Choice of Palliative Procedures for Pulmonary Atresia With Ventricular Septal Defect Patients

Start date: May 5, 2016
Phase: N/A
Study type: Interventional

The aim is to compare effective growth true hypoplastic pulmonary arteries using Right Ventricle Outflow Tract Reconstruction by femoral allogenic vein valve conduit and systemic-to-pulmonary artery shunts (modified Blalock-Taussig shunt)

NCT ID: NCT02794584 Completed - Clinical trials for Pediatric Ventricular Septal Defects

Hybrid Closure of Congenital Heart Disease

Start date: January 2011
Phase: N/A
Study type: Interventional

Ventricular septal defect (VSD) is one of the most common pediatric congenital malformations. In recent years, in view of the rapid rise of transthoracic minimally invasive hybrid closure for pediatric VSD in the clinical practice, precision assessment of perioperative its effectiveness and safety has already become an important issue that must be solved. On the basis of echocardiography, integrating with characteristics associated critical care, the investigators focus on precision assessment of perioperative effectiveness and safety of transthoracic hybrid closure for pediatric VSD, compared with conventional surgical sternotomy repair with cardiopulmonary bypass (CPB).

NCT ID: NCT02648984 Completed - Clinical trials for Pulmonary Vascular Disease

Evaluation of Dynamic Pulmonary Vascular Resistance in Patients With Closed Ventricular Septal Defect

Start date: September 2014
Phase: N/A
Study type: Interventional

Pulmonary arterial hypertension (PAH) in patients with congenital heart disease usually develops secondary to chronic volume overload of the pulmonary circulation following left to right shunt. This overload leads to elevated pulmonary artery pressure (PAP) and later to increased pulmonary vascular resistance (PVR), leading to right ventricular dysfunction, considerable morbidity and even mortality. Since PAH nowadays is mostly detected when symptoms occur and PAP are elevated, the disease already evolved to an advanced stage and treatment is often initiated too late. Our research group standardized the technique for the detection of early pulmonary vascular disease by bicycle stress echocardiography. The investigators now aim to assess this exercise technique in a group of patients with ventricular septal defect.

NCT ID: NCT02552485 Completed - Clinical trials for Atrial Septal Defects

Evaluation of Latent Pulmonary Arterial Hypertension in Congenital Shunt Lesions

Start date: January 2015
Phase: N/A
Study type: Observational

Prospective, monocentric study for the evaluation of latent pulmonary arterial hypertension in patients with congenital shunt lesions lost to follow-up. Lost to follow-up is defined as latest clinical control ≥ 5 years.

NCT ID: NCT02529111 Completed - Clinical trials for Atrial Septal Defects

Percutaneous Closure of Atrial Septal Defects in Children: Integration of 3D Echocardiography and Fluoroscopy Imaging.

CIA3DNAVIGATOR
Start date: December 2015
Phase: N/A
Study type: Interventional

The interventional catheterization allows the percutaneous treatment of congenital heart diseases as the atrial septal defect (ASD). The examination is guided by the X-rays with stochastic side effects worrying at the child's. The software "Echonavigator" allows to merge the ultrasound image and fluoroscopic. This innovative software facilitates the procedures and reduce the irradiation time in some adult procedures. The aim of this study was to validate the image fusion in children.

NCT ID: NCT02361008 Completed - Clinical trials for Heart Septal Defects, Ventricular

A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal Defect

Start date: December 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the security and validity of transesophageal echocardiography(TEE)-guided perventricular device closure(TPDC) through minithoracotomy in treatment of infundibular ventricular septal defect(IVSD) with asymmetric occluder.

NCT ID: NCT02231216 Completed - Clinical trials for Deviated Nasal Septum

Quality of Life Study About the Role of Turbinectomy in Rhinoseptoplasty

WHOQOL-BREF
Start date: March 2014
Phase: N/A
Study type: Interventional

Research Question: Performing partial turbinectomy associated with rhinoseptoplasty is responsible for an increase in quality of life related to nasal obstruction when compared to no intervention in rhinoseptoplasty inferior turbinate? - Population: patients eligible for functional rhinoseptoplasty and / or aesthetic - Intervention: surgery, turbinectomy of inferior turbinates - Comparison: the absence of intervention in inferior turbinates - Primary endpoint: Quality of life related to nasal obstruction