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Non-invasive Modulation of Autonomic Cardiac Nervous System — MSNA  

Heart Rate Variability Clinical Trial

Official title:
Effects of Non Invasive Vagus Nerve Stimulation on Heart Rate Variability in Healthy Subjects and on Muscle Sympathetic Nerve Activity

Clinical Trial Summary

To demonstrate the effect of non invasive vagus nerve (VNS) stimulation on heart rate variability and MSNA signal.

Clinical Trial Description

First part: Assessment of the muscle sympathetic nerve activity (MSNA) at baseline using microneurography performed on the superficial peroneal nerve.

Second part: Acquisition of the MSNA signal during non-invasive VNS and apnea. Non-invasive VNS is performed using several frequencies of stimulation. Maximal and voluntaries apnea are performed at the end of the expiration.

Continuous recording of the following parameters:

- non-invasive arterial blood pressure

- R-R interval

- electrocardiogram

- MSNA activity

- respiratory curve signal

- respiratory rate, oxygen saturation ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04057508
Study type Interventional
Source Université Catholique de Louvain
Contact Anaïs Gauthey, MD
Phone 027682888
Email anais.gauthey@uclouvain.be
Status Recruiting
Phase N/A
Start date June 19, 2019
Completion date December 2019
View Details
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