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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05244603
Other study ID # 10710
Secondary ID
Status Completed
Phase Early Phase 1
First received
Last updated
Start date December 1, 2021
Est. completion date December 30, 2023

Study information

Verified date April 2024
Source Utah State University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge. This proposal utilizes an established signal processing technique, currently exploited for improved understanding of speech in noise for listeners with hearing loss, to investigate its potential application to overcome speech-in-noise difficulties for listeners understanding dysarthric speech. Successful completion of this project will demonstrate proof-of-concept for the application of this signal processing technique to dysarthric speech in noise, and inform the development of an R01 proposal to perform a large-scale evaluation of the technology, and clinically meaningful implications, in a broad range of disordered speech types and severities.


Recruitment information / eligibility

Status Completed
Enrollment 447
Est. completion date December 30, 2023
Est. primary completion date December 1, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:INCLUSION CRITERIA for All Participants - Native speakers of American English - No history of speech or language impairment - No significant prior contact with persons having neurogenic speech disorders INCLUSION CRITERIA for Participants with Normal Hearing - 18 to 70 years of age - Auditory thresholds of 20 dB HL or better bilaterally at octave frequencies from 250-8000 Hz (if under 55 years of age) - Auditory thresholds of 25 dB HL or better bilaterally at octave frequencies from 250-4000 Hz (if over 55 years of age) INCLUSION CRITERIA for Participants with Sensorineural Hearing Loss - 18 to 90 years of age Exclusion Criteria: - EXCLUSION CRITERIA for All Participants - Mild or profound hearing loss - Conductive or mixed hearing loss - Asymmetric hearing loss - Obvious concomitant cognitive or mental impairment - Unable to achieve upward of 20% words correct

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Ideal binary mask
Speech in noise processed by ideal binary mask to reduce background noise

Locations

Country Name City State
United States Utah State University Logan Utah

Sponsors (1)

Lead Sponsor Collaborator
Utah State University

Country where clinical trial is conducted

United States, 

References & Publications (1)

Borrie SA, Yoho SE, Healy EW, Barrett TS. The Application of Time-Frequency Masking To Improve Intelligibility of Dysarthric Speech in Background Noise. J Speech Lang Hear Res. 2023 May 9;66(5):1853-1866. doi: 10.1044/2023_JSLHR-22-00558. Epub 2023 Mar 21 — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Percent correct speech intelligibility Percent of keywords correctly identified by the participant for the unprocessed and processed speech stimuli One hour
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