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Clinical Trial Summary

In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH. These lesions are believed to present at more advanced stages of the hearing and vestibular deterioration. Since then, other authors have described similar lesions in advanced non-genetic hearing and vestibular impairment as well. The purpose of this study is therefore to assess the radiologic investigation using CT and MR imaging of temporal bone to all subjects presenting with bilateral vestibulopathy, using the Barany criteria, compared to the p.P51S population.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04070937
Study type Observational [Patient Registry]
Source Jessa Hospital
Contact sebastien p JanssensdeVarebeke, MD
Phone 011337420
Email drsjanssens@gmail.com
Status Recruiting
Phase
Start date September 1, 2019
Completion date October 30, 2026

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