Clinical Trials Logo
  1. Home
  2. Healthy Volunteers
  3. NCT04755192
  4. Details
NCT04755192 Clinical Trial

Data Analysis of Protocol 04-N-0188: Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives

Healthy Volunteers Clinical Trial

Official title:
Data Analysis of Protocol 04-N-0188: Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT04755192
Other study ID # 10000363
Secondary ID 000363-N
Status Active, not recruiting
Phase
First received
Last updated
Start date February 11, 2021
Est. completion date June 30, 2022

Study information
Verified date February 11, 2021
Source National Institutes of Health Clinical Center (CC)
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Study Description: We want to analyze the data collected under Protocol 04-N-0188. Objectives: To assess the eye blink rate (EBR) during different behavioral conditions. Study Population: No new subjects will be enrolled. Adult (greater than or equal to 18 years old) subjects in Protocol 04-N-0188 included the following: 1. patients with craniofacial dystonia, 2. first degree relatives of patients with craniofacial dystonia, 3. age matched control group. Description of Sites/Facilities conducting research: All data analysis will take place either on the NIH Main campus or remotely using NIH-provided computers and laptops. Study Duration: 12 months.

Description:

Study Description: We want to analyze the data collected under Protocol 04-N-0188. Objectives: To assess the eye blink rate (EBR) during different behavioral conditions. Study Population: No new subjects will be enrolled. Adult (greater than or equal to 18 years old) subjects in Protocol 04-N-0188 included the following: 1. patients with craniofacial dystonia, 2. first degree relatives of patients with craniofacial dystonia, 3. age matched control group. Description of Sites/Facilities conducting research: All data analysis will take place either on the NIH Main campus or remotely using NIH-provided computers and laptops. Study Duration: 12 months.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 72
Est. completion date June 30, 2022
Est. primary completion date June 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility - INCLUSION CRITERIA: - Adults greater than or equal to 18 years old - Subjects in who participated in Protocol 04-N-0188 - Patients with craniofacial dystonia - First degree relatives of patients with craniofacial dystonia - Age matched control group. EXCLUSION CRITERIA: -Children

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States National Institute of Neurological Disorders and Stroke (NINDS) Bethesda Maryland

Sponsors (1)
Lead Sponsor Collaborator
National Institute of Neurological Disorders and Stroke (NINDS)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary assess the eye blink rate (EBR) To assess the eye blink rate (EBR) during different behavioral conditions and between the 3 groups. during the previous protocol
See also
  Status Clinical Trial Phase
Completed NCT05001152 - Taste Assessment of Ozanimod Phase 1
Completed NCT05029518 - 3-Way Crossover Study to Compare the PK (Pharmokinetics) and to Evaluate the Effect of Food on the Bioavailability Phase 1
Completed NCT04493255 - A Study to Determine the Metabolism and Elimination of [14C]E7090 in Healthy Male Participants Phase 1
Completed NCT03457649 - IV Dose Study to Assess the Safety, Tolerability, PK, PD and Immunogenicity of ARGX-113 in Healthy Volunteers Phase 1
Completed NCT00995891 - Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies
Completed NCT05050318 - Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively Phase 4
Completed NCT05043766 - Evaluation of Oral PF614 Relative to OxyContin Phase 1
Completed NCT04466748 - A Multiple Ascending Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects Phase 1
Completed NCT00746733 - Vyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC Phase 1
Recruiting NCT05929651 - Study of Immunogenicity and Safety of MenQuadfi® as a Booster Vaccine in Toddlers 12 to 23 Months, Regardless of the Quadrivalent Meningococcal Conjugate Vaccine Used for Priming in Infancy Phase 4
Completed NCT05954039 - Evaluation of the Efficacy of a Dietary Supplement on Hair Loss and Hair Aspect N/A
Completed NCT05045716 - A Study of Subcutaneous Lecanemab in Healthy Participants Phase 1
Active, not recruiting NCT02747927 - Efficacy, Safety and Immunogenicity of Takeda's Tetravalent Dengue Vaccine (TDV) in Healthy Children Phase 3
Completed NCT05533801 - A Study to Demonstrate the Bioequivalence of Lecanemab Supplied in Vials and a Single-Use Auto-Injector (AI) in Healthy Participants Phase 1
Not yet recruiting NCT03931369 - Adaptation of Thirst to a Single Administration of Tolvaptan (TOLVATHIRST) Phase 2
Completed NCT03279146 - A Single Dose Study Evaluating PK of TXL Oral Formulations in Healthy Subjects Phase 1
Completed NCT06027437 - A Study to Assess the Relative Biological Availability and the Effect of Food on the Drug Levels of Danicamtiv in Healthy Adult Participants Phase 1
Recruiting NCT05619874 - Effects of Two Virtual HIFCT Programs in Adults With Abdominal Obesity N/A
Completed NCT05553418 - Investigational On-body Injector Clinical Study N/A
Completed NCT04092712 - Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male Volunteers Phase 1