Leucine Supplementation in Young Subjects Undergoing Resistance Training

Healthy Volunteers Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02744443
• Other study ID #: LeucineUSP
• Status: Completed
• Phase: N/A
• First received: April 12, 2016
• Last updated: April 15, 2016
• Start date: January 2015
• Est. completion date: April 2016

Study information

• Verified date: April 2016
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: April 2016
• Est. primary completion date: April 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• training experience > 12 months

• no previous use of anabolic steroids

• no diagnosed diseases or injuries at the time of recruitment

• one-maximum repetition strength (1-RM) in leg press = 3.5 and = 5.0 times the body weight

Exclusion Criteria:

• use of creatine or beta-alanine supplements for the last 3 months

• use of protein or aminoacids supplements for the last 1 month

• engagement in specific dietary restrictions

• engagement in competitive sports

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)

Related Conditions & MeSH terms

• Healthy Volunteers

Intervention

Dietary Supplement:
• Leucine

• Placebo

Locations

Country	Name	City	State
Brazil	University of Sao Paulo	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	muscle cross-sectional area	B-mode ultrasound	12 weeks	No
Secondary	muscle strength	One repetition maximum (1RM) on 45º leg press machine and Muscular Endurance Test on 45º leg press machine	12 weeks	No