Healthy Volunteers Clinical Trial
Official title:
Bioavailability, Pharmacokinetics and Tissue Distribution of R-flurbiprofen Capsules in Healthy Subjects
For previous clinical trials, R-flurbiprofen has been prepared in tablet form. In this study
R-flurbiprofen, will be available as gelatine capsules.
This study aims to show the bioavailability of R-flurbiprofen when administered in gelatine
capsules. The serum availability will be determined by analysis of pharmakokinetic
(pK)-blood samples at different time points. To assess the safety of the administered
capsules adverse events will be documented.
Analysis of lipid signaling molecules in plasma will be done to assess the role of this
molecules as variable for therapeutic effects.
n/a
Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label
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