A Study of MHAA4549A in Healthy Volunteers in an Influenza Challenge Model

Status Completed

Clinical Trial Summary

This randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of MHAA4549A in healthy volunteers in an influenza challenge model. Subjects will be intranasally oculated with the challenge virus and will be randomly assigned to receive a intravenous dose of either MHAA4549A or placebo. In the stage 5 cohort, subjects will be randomly assigned to receive doses of MHAA4549A or placebo or Tamiflu (oseltamivir) orally twice daily for 5 days. All subjects in all cohorts may take Tamiflu twice daily from Day 7 to Day 11.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Healthy Volunteer

Clinical Trial Details

NCT number	NCT01980966
Study type	Interventional
Source	Genentech, Inc.
Contact
Status	Completed
Phase	Phase 2
Start date	November 25, 2013
Completion date	June 19, 2014

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