Healthy Volunteers Clinical Trial
Official title:
The Effect of Ketoconazole or Fluconazole on the Pharmacokinetics of Baricitinib in Healthy Subjects
The main purpose of this study is to look at the effect of ketoconazole and fluconazole on
how much baricitinib gets into the blood stream. The study will also look at the
tolerability of baricitinib and ketoconazole when given together and the tolerability of
baricitinib and fluconazole when given together.
Participants will be recruited into one of 2 treatment groups (Group A, Group B). Each
treatment group will participate in 2 study periods. Participants will take baricitinib
alone in one period and baricitinib with either ketaconazole or fluconazole in the other
period. This study will last approximately 7 weeks.
n/a
Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science
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