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Clinical Trial Summary

The purpose of this study is to assess the impact of sleep deprivation on subjective inspiratory endurance in healthy subjects.


Clinical Trial Description

Sleep in intensive care unit is altered and few studies have suggested that sleep deprivation (SD) could impact respiratory muscle endurance. A lack of inspiratory endurance could lengthen weaning from invasive ventilation. The purpose of this study is to confirm whether SD alters inspiratory endurance and to identify brain mechanisms involved in SD-induced decreased endurance. A group of 20 male healthy subjects will perform an inspiratory load trial after a normal sleep night and after a sleepless night. Electrophysiological parameters (EEG, motor evoked potentials) of the inspiratory motor command and sensory perceptions will be assessed before, during and after each trial. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02725190
Study type Interventional
Source Poitiers University Hospital
Contact
Status Completed
Phase N/A
Start date April 2016
Completion date December 2017

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