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Healthy Volunteers clinical trials

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NCT ID: NCT03802292 Completed - Healthy Volunteers Clinical Trials

First-In-Man, Healthy Volunteer Study to Evaluate Safety on the Use of YQ23

Start date: January 16, 2019
Phase: Phase 1
Study type: Interventional

This study is to test the safety, tolerability, pharmacokinetics (PK-the amount of study drug in the blood), and immunogenicity (how the study drug affects the immune system) of single dose and dose levels of an investigational drug called YQ23.

NCT ID: NCT03801148 Completed - Healthy Volunteers Clinical Trials

A Study to Compare the Bioavailability (BA) of Dexlansoprazole Delayed-release Capsules

Start date: January 10, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the BA of 30 or 60 milligram (mg) dexlansoprazole capsule manufactured at TOB (Takeda GmbH Plant Oranienburg) to the corresponding 30 or 60 mg dexlansoprazole manufactured at TPC (Takeda Pharmaceutical Company Ltd.).

NCT ID: NCT03798912 Completed - Healthy Volunteers Clinical Trials

A First-in-Human Study of the RaniPill, an Oral Drug Delivery Platform

RaniPill
Start date: July 9, 2019
Phase: Phase 1
Study type: Interventional

The objective of this study is to ascertain the safety, tolerability and performance of the RaniPill capsule in healthy volunteers

NCT ID: NCT03798262 Completed - Clinical trials for Healthy Volunteers, Gluten

Effect of Acute and Sub-acute Administration of Gluten on Extra-intestinal and Gastrointestinal Symptoms in Healthy Subjects

Start date: February 16, 2017
Phase: N/A
Study type: Interventional

The investigators will investigate the effects of acute and sub-acute administration of gluten on mood, intestinal permeability, gastrointestinal symptoms and gut peptide levels in healthy volunteers (HV).

NCT ID: NCT03796910 Completed - Healthy Volunteers Clinical Trials

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Start date: December 18, 2018
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics (PK) following single and multiple ascending dose administration of SPR720 administered orally in healthy volunteers.

NCT ID: NCT03796351 Completed - Healthy Volunteers Clinical Trials

Pharmacodynamic and Safety of MT10107(Botulinum Type A Neurotoxin) in Comparison to BOTOX®

Start date: September 2012
Phase: Phase 1
Study type: Interventional

This study design is a randomized, double-blind, intra-individual controlled, single-center, phase 1 healthy volunteer study. Subjects who voluntarily signed the informed consent and are judged to be eligible for this study will be intramuscularly injected with the study drug or the comparator at a randomized unit(2U, 5U, 10U, 20U, 30U) in each site of the Extensor digirotum brevis. Thereafter, follow-up visits will be made 14 days, 30days, 60days, 90days and pharmacodynamic and safety assessments will be conducted for total 90days.

NCT ID: NCT03796260 Completed - Healthy Volunteers Clinical Trials

A Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed Conditions in Healthy Participants

Start date: January 9, 2019
Phase: Phase 1
Study type: Interventional

This study aims to investigate the relative bioavailability, safety, and tolerability of entrectinib capsule formulations F1 and F06 under fed conditions in healthy adult male and female participants.

NCT ID: NCT03796013 Completed - Healthy Volunteers Clinical Trials

A Study to Investigate the Bioequivalence of Two Different Forms of Entrectinib (Forms A and C) Under Fasted Conditions in Healthy Subjects

Start date: January 10, 2019
Phase: Phase 1
Study type: Interventional

This study aims to demonstrate similarities between two different forms of entrectinib (A and C) when administered under fasted conditions in healthy subjects.

NCT ID: NCT03795519 Completed - Healthy Volunteers Clinical Trials

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers

Start date: January 17, 2019
Phase: Phase 1
Study type: Interventional

The primary objective is to characterize the pharmacokinetics (PK) of olinciguat and total radioactivity and to assess the elimination of total radioactivity from a single oral dose of [14C]-olinciguat.

NCT ID: NCT03795142 Completed - Healthy Volunteers Clinical Trials

A First-time-in-human Study of BGB149

Start date: December 19, 2018
Phase: Early Phase 1
Study type: Interventional

This clinical trial is a Phase I, first-in-human. The study is designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and immunogenicity of BGB149 after single IV doses in healthy male and female subjects. Multiple dose levels will be explored.