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Healthy Volunteers clinical trials

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NCT ID: NCT04863105 Completed - Healthy Volunteers Clinical Trials

Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers

Start date: November 24, 2017
Phase: Phase 1
Study type: Interventional

An open, randomized, single-dose, three-cycle, three-sequence crossover study was conducted in 36 healthy volunteers under fasting condition to evaluate the bioequivalence of two abiratone acetate tablets.

NCT ID: NCT04862338 Completed - Healthy Volunteers Clinical Trials

Pharmacodynamics and Tolerance of Nicotinamide Mononucleotide (NMN, 400mg/Day) in Healthy Adults

Start date: April 26, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the physiological and/or biological actions of nicotinamide mononucleotide (NMN-C) in healthy adults receiving a repeated-dose over the course of 28 days by studying the tolerance and pharmacodynamics of this product.

NCT ID: NCT04857710 Completed - Healthy Volunteers Clinical Trials

Chronic Effects of Wide-pulse Neuromuscular Electrostimulation on Neuromuscular and Functional Properties in Healthy Subjects

ELECTRO-WP
Start date: May 5, 2021
Phase: N/A
Study type: Interventional

Neuromuscular electrostimulation (NMES) is a technique used in the clinical and training fields to increase the strength of a muscle group.The recent use of wide-pulse (WP) stimulations allows, in addition to the direct activation of the muscle fibers, the use of sensory pathways. This more global solicitation of the neuromuscular system (i.e. information going back to the spinal cord and even to the brain) prejudges more nervous adaptations and therefore a greater functional benefit. The first aim of this study is to evaluate and compare the force gains induced by 2 NMES training programs (CONV, WP) applied on knee extensors in healthy subjects for 6 weeks.The second aim is to understand the neuromuscular adaptations involved in these gains, as well as the functional benefit resulting from these improvements.

NCT ID: NCT04856098 Completed - Healthy Volunteers Clinical Trials

Absorption of Indacaterol and Glycopyrronium From Ultibro Breezhaler

FINDA
Start date: May 7, 2021
Phase: Phase 1
Study type: Interventional

The objective of this study is to assess pharmacokinetics (PK) of indacaterol and glycopyrronium, and methodology and practical arrangements for future studies.

NCT ID: NCT04856007 Completed - Healthy Volunteer Clinical Trials

A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects.

Start date: April 12, 2021
Phase: Phase 1
Study type: Interventional

To assess the bioequivalence between dapagliflozin/metformin XR FDC tablet and co-administration of dapagliflozin and metformin XR tablets.

NCT ID: NCT04854174 Not yet recruiting - Healthy Volunteers Clinical Trials

A Food Effect Study of ZN-d5 in Healthy Female Volunteers

Start date: June 4, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center, sequential, open-label, food effect study to determine the comparative bioavailability of ZN-d5 under fasting and fed conditions, following single-dose oral administration of ZN-d5. The study will be comprised of a pre-study screening, followed by administration of a single dose of ZN-d5 under fasted conditions, a washout period, administration of a single dose of ZN-d5 under fed conditions, and a follow-up period.

NCT ID: NCT04850144 Completed - Healthy Volunteers Clinical Trials

Pharmacokinetic Study Comparing Tiotropium Easyhaler® and Spiriva® HandiHaler®

TESSA
Start date: April 26, 2021
Phase: Phase 1
Study type: Interventional

Absorption of inhaled tiotropium is compared between five Tiotropium Easyhaler product variants and Spiriva capsules inhaled via HandiHaler without charcoal. Absorption of tiotropium is compared between one Easyhaler product variant administered with and without charcoal.

NCT ID: NCT04849559 Completed - Healthy Volunteer Clinical Trials

Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers

Start date: February 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the effects of tradipitant relative to placebo on satiation, gastric volume, gastric accommodation, and gastric emptying in healthy volunteers.

NCT ID: NCT04849299 Completed - Clinical trials for Healthy Volunteer Study

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Start date: April 18, 2021
Phase: Phase 1
Study type: Interventional

This study will determine the effect of cyclosporine on the PK of AT-527 (R07496998) in healthy male subjects

NCT ID: NCT04845321 Terminated - Healthy Volunteers Clinical Trials

VNRX-9945 Safety and Pharmacokinetics in Healthy Adult Volunteers

Start date: June 23, 2021
Phase: Phase 1
Study type: Interventional

This is a 2-part first-in-human dose-ranging study to evaluate the safety and pharmacokinetics of escalating doses of VNRX-9945.