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Healthy Volunteers clinical trials

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NCT ID: NCT04836572 Completed - Clinical trials for Healthy Volunteer Study

An Open-label, Non Significant Risk, Adhesive Wear Validation Study for the On Body Drug Delivery Device Component of the SQIN-01 Furosemide Infusor (Infusor Device)

Start date: January 20, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to test the adequacy, performance and skin reactivity of the adhesive tape to be utilized in the to-be-marketed Device. The present study will examine adhesive hold performance, re-use protection (i.e. adhesive re-application) and skin reactivity/tolerability of the proposed commercial adhesive tape (i.e. within the Test Infusor Device; TID). As the purpose of the study is to assess adhesive performance which does not require activation of the device. Hence in this study no canula will be deployed (no skin penetration) and no delivery of the drug or other fluids.

NCT ID: NCT04833049 Completed - Healthy Volunteers Clinical Trials

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Start date: April 14, 2021
Phase: Phase 1
Study type: Interventional

The aim of this study is to understand how TAK-994 is processed by the body. This study will require participants to stay at the clinical research unit for 3 weeks to be monitored after receiving TAK-994.

NCT ID: NCT04829305 Completed - Healthy Volunteers Clinical Trials

A Trial of SHR2285 in Healthy Subjects

Start date: May 20, 2021
Phase: Phase 1
Study type: Interventional

This is a phase 1 open-label study

NCT ID: NCT04823988 Completed - Healthy Volunteer Clinical Trials

Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic

Start date: April 13, 2021
Phase:
Study type: Observational

Background: COVID-19 has caused a high rate of deaths. The steps taken to control its spread have caused social isolation, changes in lifestyle, economic turmoil, and increased work-related stress. As a result, there has been a rise in mental and physical health problems. These burdens are particularly severe for people with a history of mental illness. Researchers want to learn more about the relationship between stressors related to COVID-19 and self-rated measures of anxiety and other variables. Objective: To better understand the impact of this stressful time on people s lives and families. Also, to learn the strategies people have been using to deal with the COVID-19 pandemic. Eligibility: Adults ages 18 and older. Design: This is an online study. Participants will fill out surveys online. The surveys will ask about their mood, anxiety, medical history, substance use, and COVID-19 stressors. Participants will complete an online task. For the task, they will stare at the center of a computer screen. When they see certain images, they will indicate the location of that image as quickly as possible. It will take about 1.5 hours for participants to complete the surveys and tasks. They may be contacted again if additional data is needed. Some participants may have taken part in other NIH studies. If so, their new data may be linked to their previously collected data. ...

NCT ID: NCT04820439 Completed - Healthy Volunteers Clinical Trials

Pharmacokinetic Study of Recombinant Monoclonal Antibody Against Human Epidermal Growth Factor Receptor Injection

Start date: October 13, 2020
Phase: Phase 1
Study type: Interventional

This study was designed as a randomized, double-blind, parallelity-controlled study.Eighty-eight healthy male subjects (44 in each group) will be enrolled in this study.The aim of this clinical trial is to evaluate pharmacokinetic similarity between recombinant monoclonal antibody against human epidermal growth factor receptor injection (HS627) and Perjeta ® in a single intravenous infusion in healthy male subjects.

NCT ID: NCT04817202 Completed - Healthy Volunteers Clinical Trials

Safety, Tolerability, Pharmacokinetics of hzVSf-v13 in Healthy Adults (Intravenous and Subcutaneous Administration)

Start date: September 16, 2020
Phase: Phase 1
Study type: Interventional

Assessment of the safety, tolerability and pharmacokinetics (PK) characterization of hzVSF-v13 with single and multiple doses (intravenous and subcutaneous) compared to placebo in healthy subjects.

NCT ID: NCT04813809 Completed - Healthy Volunteers Clinical Trials

A Clinical Investigation With BARRIER® EasyWarm®

EasyWarm01
Start date: April 14, 2021
Phase: N/A
Study type: Interventional

This investigation is a prospective, open, non-comparative, single-center investigation with the aim to investigate the effect of BARRIER EasyWarm active self-warming blanket on skin- and body core temperatures. The investigation will enroll approximately 20 healthy volunteers in one investigation site and each subject will be evaluated for up to 10 hours in one visit.

NCT ID: NCT04812080 Completed - Clinical trials for Healthy Volunteers From Racial/Ethnic Minority Populations

EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations

Start date: August 18, 2021
Phase: N/A
Study type: Interventional

The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER. The study will aim to recruit healthy individuals from racial/ethnic minority populations.

NCT ID: NCT04811625 Completed - Healthy Volunteers Clinical Trials

Pharmacodynamic and Pharmacokinetic Study of PL-ASA

Start date: April 28, 2021
Phase: Phase 4
Study type: Interventional

A randomized, open-label, 2-way crossover pharmacodynamic and pharmacokinetic study of a novel pharmaceutical lipid-aspirin complex formulation (PL-ASA) at an 81 mg dose

NCT ID: NCT04807751 Completed - Healthy Volunteers Clinical Trials

Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib Cream

Start date: March 25, 2021
Phase: Phase 1
Study type: Interventional

Participants will have study medicine applied by site staff- delgocitinib cream or vehicle, and then exposed to UV light. The trial is designed to find out if delgocitinib cream can cause skin photoallergy after UV-light exposure in people with healthy skin.