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Healthy Volunteers clinical trials

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NCT ID: NCT01903434 Completed - Healthy Volunteers Clinical Trials

A Study of Evacetrapib (LY2484595) in Healthy Participants

Start date: July 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure and compare the amounts of the study drug evacetrapib found in the blood after taking two different formulations. The study has 3 periods. Participants will take each formulation by mouth at least once. A minimum of 14 days will pass between study drug doses. The safety and tolerability of the study drug will also be examined. Information about any side effects that may occur will also be collected. This study will last approximately 6 weeks.

NCT ID: NCT01902121 Completed - Healthy Volunteers Clinical Trials

Compare the Same Dosage of Insulin Using a Combination of Cartridges, 30 Units as 2 Cartridges vs. 1 Cartridge

Start date: August 2013
Phase: Phase 1
Study type: Interventional

A Phase 1, open-label, randomized, crossover study in 36 healthy normal volunteers (HNVs) to evaluate the bioequivalence of TI Inhalation Powder delivered using the Gen2 Inhaler and administered as one 30 U cartridge versus a combination of one 10 U cartridge and one 20 U cartridge.

NCT ID: NCT01901198 Completed - Healthy Volunteers Clinical Trials

Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase I Study in Chinese Healthy Volunteers

Start date: April 2013
Phase: Phase 1
Study type: Interventional

This study will evaluate safety, tolerability, pharmacokinetics and pharmacodynamics of Recombinant Human Serum Albumin/interferon alpha2a Fusion Protein single dose in Chinese healthy volunteers.

NCT ID: NCT01901159 Completed - Healthy Volunteer Clinical Trials

A Study of RO4995819 to Assess Bioavailability and Safety in Healthy Volunteers

Start date: June 2013
Phase: Phase 1
Study type: Interventional

This randomized, open-label, cross-over study will assess the bioavailability and safety of RO4995819 in healthy volunteers. Volunteers will receive two different formulations (tablet and capsule) of the study drug under fed and fasting conditions.

NCT ID: NCT01897779 Completed - Healthy Volunteers Clinical Trials

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2014 and RPX7009 in Healthy Adult Subjects

Start date: July 2013
Phase: Phase 1
Study type: Interventional

RPX7009 (beta-lactamase inhibitor) is being studied in combination with a carbapenem (RPX2014) to treat bacterial infections, including those due to multi-drug resistant bacteria.

NCT ID: NCT01897493 Completed - Healthy Volunteers Clinical Trials

A Study of Evacetrapib and Digoxin in Healthy Participants

Start date: July 2013
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to determine how much digoxin gets into the blood stream and how long it takes the body to get rid of it when given with the study drug evacetrapib. This study will also look at the effect of evacetrapib on the removal of digoxin from the body by the kidneys. Information about any side effects that may occur will be collected. This study will last approximately 33 days for each participant, not including screening.

NCT ID: NCT01897389 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Relative Bioavailability of 4 New Abiraterone Acetate Tablet Formulations With Respect to the Current Commercial Abiraterone Acetate Tablet Under Fasted Conditions in Healthy Male Participants

Start date: July 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the relative bioavailability of 4 new formulations of abiraterone acetate compared to the current commercial formulation.

NCT ID: NCT01896726 Completed - Healthy Volunteers Clinical Trials

A Study of Baricitinib and Birth Control Pills in Healthy Females

Start date: July 2013
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to find out how the body absorbs and breaks down a common birth control pill called Microgynon when it is given with the study drug called baricitinib. Safety and the body's ability to tolerate baricitinib and Microgynon will also be studied. The study will last approximately 6 weeks for each participant.

NCT ID: NCT01896323 Completed - Healthy Volunteers Clinical Trials

CC-223 and Ketoconazole Drug-Drug Interaction Study

Start date: July 1, 2013
Phase: Phase 1
Study type: Interventional

This is a single-center open-label study to compare how CC-223 (the study drug being investigated) interacts with the drug ketoconazole.

NCT ID: NCT01894399 Completed - Healthy Volunteers Clinical Trials

Study to Evaluate a Pharmacokinetic of HM61713 in Healthy Male Subjects

Start date: September 2013
Phase: Phase 1
Study type: Interventional

Study Design - Open, escalating single-dose design. - 7 ascending dose cohorts - In each cohorts, subjects will receive a single dose of HM61713. - Main objective of this study is to evaluate the pharmacokinetics of HM61713 tablet.