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Healthy Volunteers clinical trials

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NCT ID: NCT02136316 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Multiple Ascending Doses of ASP7962 in Healthy Subjects

MAD
Start date: May 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability as well as the pharmacokinetics of increasing oral multiple doses of ASP7962 in healthy young male and female subjects.

NCT ID: NCT02135965 Completed - Healthy Volunteers Clinical Trials

Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate

CALM
Start date: April 2009
Phase: Phase 0
Study type: Interventional

The purpose of this study is to define a ratio of Caffeine and albuterol that gives a synergistic increase in metabolic rate.

NCT ID: NCT02134964 Completed - Healthy Volunteers Clinical Trials

Phase 1 Safety and PK Study of OLT1177 Capsules

Start date: June 2014
Phase: Phase 1
Study type: Interventional

This study is a randomized, placebo-controlled, sequential ascending-dose study of healthy volunteers after administration of single or multiple dose(s) of investigational drug (OLT1177 Caps or Placebo Caps). A total of 36 subjects will be enrolled across 6 cohorts, and subjects in each cohort will be randomized in a ratio of 5 active to 1 placebo.

NCT ID: NCT02134834 Completed - Healthy Volunteers Clinical Trials

A Phase I Study to Assess Safety, Tolerability and Pharmacokinetics of OP0595

Start date: May 2014
Phase: Phase 1
Study type: Interventional

The objectives of this study are to assess the safety, tolerability and pharmacokinetic profile of OP0595 administered intravenously to healthy male, Caucasian, adult subjects at single escalating doses.

NCT ID: NCT02133937 Completed - Healthy Volunteer Clinical Trials

A Study Investigating the Bioavailability of a High Concentration Liquid Formulation Versus a Reference Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Start date: April 2014
Phase: Phase 1
Study type: Interventional

This single-center, randomized open-label, single-dose, parallel group study will investigate the relative bioavailability of a high concentration liquid formulation (HCLF) versus the reference lyophilized formulation (LyoF) of gantenerumab. Healthy volunteers will be randomized 1:1 to receive single-dose gantenerumab by subcutaneous injection.

NCT ID: NCT02126514 Completed - Healthy Volunteers Clinical Trials

A Phase I, Open-Label, Single-Center Study to Assess the Absorption, Metabolism, and Excretion of [14C]-AZD3293

AZD3293hADME
Start date: May 2014
Phase: Phase 1
Study type: Interventional

This study will be an open-label, non-randomized, absorption, metabolism, and excretion study to evaluate the mass balance, metabolite profiles, and rates and routes of elimination of [14C]-AZD3293 and derived metabolites following administration as a single 100-mg (containing approximately 150 µCi) oral dose (as an oral solution)

NCT ID: NCT02125422 Completed - Healthy Volunteers Clinical Trials

Neurophysiological Study of tDCS Effects in Healthy Volunteers

tDCSHV
Start date: November 2013
Phase: Phase 1
Study type: Interventional

Transcranial direct current stimulation is a tool to modulate cortical excitability.

NCT ID: NCT02123472 Completed - Healthy Volunteers Clinical Trials

A Study of Cephalexin Liquid for Pediatrics in Healthy Adults Participants

Start date: May 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare two different preparations of an antibiotic called cephalexin to determine if they are essentially the same. The study has two periods. Participants will receive one preparation of cephalexin in each period. At least 7 hours will pass between the study periods. The study is expected to last about 2 days for each participant, not including screening or follow-up.

NCT ID: NCT02123459 Completed - Healthy Volunteers Clinical Trials

A Study of Cephalexin Suspension in Healthy Participants

Start date: May 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare two different preparations of an antibiotic called cephalexin to determine if they are essentially the same. The study has two periods. Participants will receive one preparation of cephalexin in each period. At least 7 hours will pass between the study periods. The study is expected to last about 2 days for each participant, not including screening or follow-up.

NCT ID: NCT02123446 Completed - Healthy Volunteers Clinical Trials

A Study of Cephalexin Capsules in Healthy Participants

Start date: April 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare two different preparations of an antibiotic called cephalexin in capsules to determine if they are essentially the same. The study has two periods. Participants will receive one preparation of cephalexin in each period. At least 7 hours will pass between the study periods. The study is expected to last about 2 days for each participant, not including screening or follow-up.