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Clinical Trial Summary

High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute respiratory distress syndrome (ARDS) after conventional mechanical treatment fails. ventilation. Non-invasive high-frequency oscillatory ventilation (nHFOV) combines the advantages of HFOV and non-invasive ventilation methods, and has become a research hotspot in this field. Recommended to avoid intubation after failure of conventional non-invasive ventilation therapy. There is a lack of large-scale clinical trials systematically exploring its efficacy for intubation therapy. The increasing clinical application of nHFOV has also enriched its application in the treatment of other diseases. Human-machine asynchrony during non-invasive ventilation will seriously affect its efficacy, but no one has reported on the research related to nHFOV human-machine asynchrony.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05448417
Study type Interventional
Source Guangzhou Institute of Respiratory Disease
Contact Jianyi Niu, MD
Phone +8617825846046
Email niujianyi001@163.com
Status Not yet recruiting
Phase N/A
Start date July 15, 2022
Completion date July 1, 2023

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