View clinical trials related to Healthy Subjects.
Filter by:Single usage, open label study in 16 adult healthy males. Eligible subjects will receive a single usage of the investigational device. Retention of the radiolabeled device will be monitored using gamma scintigraphy.
This study is to determine the effect of single and multiple oral doses of mifepristone on the pharmacokinetics of a single oral dose of fluvastatin administered to healthy volunteers.
Human Multidrug Related Protein 2 (MRP2) excretes several drugs and could therefore modulate their elimination. Individual's MRP2 activity is under genetic control. Thus it would be very useful to get an easily measurable biomarker reflecting individual's MRP2 activity. We aimed to investigate the ratio of urinary coproporphyrins I and III (UCP(I/I+III), known to be increased in patients with mutations in MRP2/ABCC2 gene.
Since Tai Chi Chuan (TCC) training has been shown to be beneficial to the cardiopulmonary function of the subject, TCC might have a beneficial effect on the pulmonary function, autonomic nervous modulation, lipid profile, and cytokines production in the aged subjects.
The primary objective of this pilot study is to establish a model of neutrophil airway inflammation for future testing of anti-inflammatory substances in an early stage of clinical development. Moreover, the suitability of an electronic nose for early detection and diagnosis of airway inflammation will be determined.
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D. It is not known what levels of vitamin D are needed to allow the body to make this protein. Nor is it known if giving vitamin D to people who are found to be deficient will help boost levels of hCAP18. This study aims to clarify the relationship between vitamin D levels and hCAP18.
This is a single ascending dose study of HSD-016 to provide the initial assessment of the safety, tolerability, how the drug is absorbed and eliminated, and it's effect on the body in Japanese male subjects.
This is a single ascending dose study of HSD-016 to provide the initial assessment of the safety, tolerability, how the drug is absorbed and eliminated, and its effect on the body.
Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health. The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise. The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training
A study in healthy volunteers to determine whether there is a drug interaction between GSK1349572 and tenofovir