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Healthy Subjects clinical trials

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NCT ID: NCT03221374 Completed - Healthy Subjects Clinical Trials

Mind-body Awareness Training and Brain-computer Interface

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Mind-Body Awareness Training (MBAT), in the forms of various yoga and meditative practices, has become increasingly prevalent due to an increase in awareness of the potential health benefits, and improvements in concentration that this training can provide to practitioners. In the present study, the role of Mind-Body Awareness Training (MBAT) in the initial learning of a sensorimotor (SMR) based Brain-Computer Interface (BCI) is being investigated. The hypothesis is that MBAT will improve performance in SMR based BCI.

NCT ID: NCT03217942 Completed - Healthy Subjects Clinical Trials

Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model

Start date: July 1, 2017
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to investigate and determine the time course and distribution on muscle hyperalgesia and muscle pain in a repeated, low dose NGF model. It is hypothesized that low dosages i.m injections of NGF are able to induce mechanical hyperalgesia and muscle soreness in a same manner (effect of duration) as for dosages previously used in NGF studies. Furthermore, it is also speculated if several injections of low dose NGF into the muscle combined are able to course immediate pain sensation and spreading of muscle hypersensitivity.

NCT ID: NCT03215966 Completed - Healthy Subjects Clinical Trials

A Study to Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects

Start date: August 7, 2017
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to demonstrate that macitentan and tadalafil administered as a fixed combination is bioequivalent to both compounds given as separate tablets given at the same doses as in the fixed combination (i.e. whether the amounts of macitentan and tadalfil which reach the blood are comparable).

NCT ID: NCT03178448 Active, not recruiting - Healthy Subjects Clinical Trials

PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events

PRECISE
Start date: May 15, 2017
Phase:
Study type: Observational

The objective of this study is to characterize the prevalence of clinical or subclinical polyvascular lesions and 4-year progression rate of plaque in intracranial and carotidal arteries in a Chinese community population using vascular imaging techniques; to investigate the both traditional and emerging genetic, metabolomic, and environmental risk factors of presence and progression of intracranial and carotidal plaque; and to investigate the association between polyvascular lesions and future risk of cognitive impairment, cardio-/cerebrovascular events and death.

NCT ID: NCT03173625 Completed - Healthy Subjects Clinical Trials

A Study Conducted in Healthy Male Subjects to Investigate the Safety and Tolerability of AC-76, Its Fate in the Body, and Its Effect on the Body

Start date: November 29, 2016
Phase: Phase 1
Study type: Interventional

The main objective of the study is to investigate the safety and tolerability of single ascending doses of AC-076 administered as subcutaneous injection

NCT ID: NCT03165097 Completed - Healthy Subjects Clinical Trials

Study to Evaluate Safety and Tolerability of ACT-709478 in Healthy Subjects

Start date: July 7, 2017
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to evaluate the safety and tolerability of ascending multiple doses of ACT-709478 in healthy male and female subjects

NCT ID: NCT03165071 Completed - Healthy Subjects Clinical Trials

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Start date: June 3, 2017
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to investigate the fate of ACT-132577 in healthy subjects and in people with severe kidney disease

NCT ID: NCT03128476 Completed - Healthy Subjects Clinical Trials

Effects of Essence of Chicken on Physical Fatigue, Working Memory and Attention

Start date: March 3, 2016
Phase: N/A
Study type: Interventional

In Southeast Asia, Essence of Chicken, a chicken-meat-extract, is a popular beverage and is consumed as a traditional remedy for several ailments, including the use as a nutritional supplement for sickness, enhancement of mental efficiency, and recovery from mental fatigue. While the elderly use it as a nutritional supplement, students use it for relief from anxiety during exam times. The present study is conducted in order to assess the effects of BEC on various physical and mental parameters including physical fatigue, working memory and attention, mood and stress, in comparison to placebo.

NCT ID: NCT03107403 Completed - Healthy Subjects Clinical Trials

Dreams and Bereavement

DreamDeath
Start date: October 9, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to investigate a possible role of dreaming in emotion regulation testing whether dreaming of a close relative recently deceased is correlated with a positive evolution of the bereavement process

NCT ID: NCT03101189 Completed - Healthy Subjects Clinical Trials

A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects

Start date: March 15, 2017
Phase: Phase 1
Study type: Interventional

So far, ACT-541468 has been studied mainly in Caucasian subjects. The present study will bridge results obtained in Caucasian subjects to those in Japanese subjects.