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Healthy Subjects clinical trials

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NCT ID: NCT03365739 Completed - Healthy Subjects Clinical Trials

Bioavailability and Pharmacokinetics of Mango

MG
Start date: November 17, 2017
Phase: N/A
Study type: Interventional

The primary objectives of the study are: 1. To investigate the relative bioavailability and absorption/kinetic profile of phytochemicals after acute consumption of mango pulp. 2. To study the systemic accumulation or generation of new mango pulp phytochemicals /their metabolites in blood after regular mango intake for an extended time frame. 3. To enhance the bioavailability of polyphenols in mango pulp by addition of Vitamin C to the mango pulp.

NCT ID: NCT03361540 Completed - Healthy Subjects Clinical Trials

ASP8302 Single and Multiple Ascending Oral Dose Study in Non-elderly Healthy Japanese Subjects

Start date: November 14, 2017
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate the safety, tolerability and pharmacokinetic of single/multiple ascending oral doses of ASP8302 in non-elderly healthy Japanese male and female subjects.

NCT ID: NCT03359291 Completed - Healthy Subjects Clinical Trials

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Start date: November 3, 2017
Phase: Phase 1
Study type: Interventional

The aim of this Phase 1 trial is to study a potential drug-drug interaction between macitentan and rosuvastatin, a model substrate of various transporter proteins (e.g. in the gut).

NCT ID: NCT03347331 Completed - Healthy Subjects Clinical Trials

[18F]-F13640 as a New Brain Radiopharmaceutical

F13640
Start date: April 23, 2018
Phase: Early Phase 1
Study type: Interventional

This clinical assay is designed to validate that [18F]F13640 as a radiotracer of 5-HT1A functional receptors. A first group of healthy subjects underwent a PET scan with arterial blood sampling to determine the kinetic model of the tracer. A second group of healthy subjects underwent a classical test-retest study (i.e two distant PET scans) to determine the reproducibility of measures.

NCT ID: NCT03339752 Completed - Healthy Subjects Clinical Trials

A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin

Start date: October 30, 2017
Phase: Phase 1
Study type: Interventional

A study in healthy male subjects to investigate whether administration of ACT-541468 can affect the fate in the body (amount and time of presence in the blood) of rosuvastatin

NCT ID: NCT03331900 Completed - Healthy Subjects Clinical Trials

Study of COR388 HCl in Healthy Subjects

Start date: December 11, 2017
Phase: Phase 1
Study type: Interventional

The study is a randomized, double-blind, placebo-controlled, dose escalation, first-in-human trial of the safety and tolerability of COR388 HCl in healthy male and female subjects.

NCT ID: NCT03330327 Completed - Healthy Subjects Clinical Trials

Molar Potency Study of HM12470 in Healthy Subjects

Start date: March 30, 2015
Phase: Phase 1
Study type: Interventional

This is a phase 1 study to assess and compare molar potency of HM12470 and regular human insulin in healthy subjects.

NCT ID: NCT03319706 Completed - Healthy Subjects Clinical Trials

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Olmesartan Medoxomil Tablets Under Fed Conditions

Start date: August 2010
Phase: Phase 1
Study type: Interventional

Subjects to compare the single dose bioavailability of Torrent's Olmesartan Medoxomil Tablets 40 mg and Benicar® 40 mg Tablets of Daiichi Sankyo Inc., USA. Dosing periods of studies were separated by a washout period of 7 days.

NCT ID: NCT03318354 Completed - Healthy Subjects Clinical Trials

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Olmesartan Medoxomil Tablet Under Fasting Conditions

Start date: May 2010
Phase: Phase 1
Study type: Interventional

Subjects to compare the single dose bioavailability of Torrent's Olmesartan Medoxomil Tablets 40 mg and Benicar 40 mg Tablets of Daichi Sankyo Inc. USA. Dosing periods of studies were separated by a washout period of 7 days.

NCT ID: NCT03309241 Completed - Healthy Subjects Clinical Trials

First In Human, Single Escalating Oral Dose Study Of PF-06882961 In Healthy Adult Subjects

Start date: October 17, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single oral doses of PF-06882961 in healthy adult subjects. This is the first clinical study of PF-06882961.