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Healthy Subjects clinical trials

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NCT ID: NCT06233058 Not yet recruiting - Healthy Subjects Clinical Trials

Drospirenone (3 mg) + Ethinyl Estradiol (0.03 mg) Tablets Relative to Yasmin®

Start date: March 5, 2024
Phase: Phase 1
Study type: Interventional

The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose. The study will be randomized, open-label, single dose, two way crossover design with two-period, two-treatment and two-sequence under fasting condition and at least 28 days washout period between the doses.

NCT ID: NCT06233045 Not yet recruiting - Healthy Subjects Clinical Trials

Dapagliflozin Tablet 10 mg Relative to Forxiga® Tablets 10 mg

DAP-030-23
Start date: July 23, 2024
Phase: Phase 1
Study type: Interventional

The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose. The study will be randomized, open-label, single dose, two way crossover design with two-period, two-treatment and two-sequence under fasting condition and at least 5 days washout period between the doses.

NCT ID: NCT06232239 Not yet recruiting - Healthy Subjects Clinical Trials

Empagliflozin 10 mg Tablets Relative to Jardiance 10 mg

Start date: February 27, 2024
Phase: Phase 1
Study type: Interventional

The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose. The study will be randomized, open-label, single dose, two way crossover design with two-period, two-treatment and two-sequence under fasting condition and at least 7 days washout period between the doses.

NCT ID: NCT06110338 Not yet recruiting - Healthy Subjects Clinical Trials

Safety and Tolerance Study of IBI355 in Health Volunteers

Start date: October 31, 2023
Phase: Phase 1
Study type: Interventional

This study is being done to find out if IBI355 is safe and tolerance in health volunteers. The study will test increasing single doses of IBI355 given to adult health volunteers. The goal is to confirmed the safety of the highest dose of IBI355 or to find out the highest dose of IBI35 that can be given to health volunteer that dose not cause unacceptable side effects. Different dose regimens will be evaluated. The pharmacokinetics and ADA of IBI355 will also be evaluated.

NCT ID: NCT05586568 Not yet recruiting - Healthy Subjects Clinical Trials

Drug-drug Interaction Study of XZP-3621 Tablet

Start date: November 15, 2022
Phase: Phase 1
Study type: Interventional

This is an open-label, single center, 2 period, one sequence study to investigate the potential drug drug interaction between itraconazole or rifampin or esomeprazole and XZP-3621 tablet.

NCT ID: NCT05448417 Not yet recruiting - Healthy Subjects Clinical Trials

Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects

Start date: July 15, 2022
Phase: N/A
Study type: Interventional

High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute respiratory distress syndrome (ARDS) after conventional mechanical treatment fails. ventilation. Non-invasive high-frequency oscillatory ventilation (nHFOV) combines the advantages of HFOV and non-invasive ventilation methods, and has become a research hotspot in this field. Recommended to avoid intubation after failure of conventional non-invasive ventilation therapy. There is a lack of large-scale clinical trials systematically exploring its efficacy for intubation therapy. The increasing clinical application of nHFOV has also enriched its application in the treatment of other diseases. Human-machine asynchrony during non-invasive ventilation will seriously affect its efficacy, but no one has reported on the research related to nHFOV human-machine asynchrony.

NCT ID: NCT05371379 Not yet recruiting - Healthy Subjects Clinical Trials

Multiple Ascending Dose Study of CM338 in Healthy Volunteers

Start date: June 1, 2022
Phase: Phase 1
Study type: Interventional

This study was a multi-center, randomized, double blind, placebo-controlled, single-dose, dose escalation Phase I study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of CM338 with multiple dosing in healthy subjects.

NCT ID: NCT05347758 Not yet recruiting - Healthy Subjects Clinical Trials

A Phase I Single- and Multiple- Ascending Dose and Food Effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7535 in Healthy Subjects

Start date: May 1, 2022
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blinded, placebo-controlled study to evaluate the safety, tolerability, Pharmacokinetics and Pharmacodynamics of single ascending dose (Part A) and multiple ascending dose (Part B) of HRS-7535 in healthy subjects.

NCT ID: NCT04977570 Not yet recruiting - Healthy Subjects Clinical Trials

A Study of SYHA1805 in Healthy Subjects

Start date: July 2021
Phase: Phase 1
Study type: Interventional

This is a Phase Ib study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple-dose of SYHA1805.

NCT ID: NCT04645901 Not yet recruiting - Healthy Subjects Clinical Trials

A Study of SYHA1805 in Healthy Adult Subjects

Start date: December 2020
Phase: Phase 1
Study type: Interventional

This is a three-part Phase Ia study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single ascending doses of SYHA1805.