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Clinical Trial Summary

Reality-monitoring is a crucial cognitive process in daily life to remember the source of an information. Deficits of reality-monitoring have been shown into the continuum of schizophrenia, suggesting a preexisting alteration in population at-risk for psychosis that will be exacerbated during psychotic transition. It is admitted that stress plays a crucial role in the psychotic transition and can alter cognitive performances. However, less is known about the effects of stress on reality-monitoring, even though this process appears to be central in psychotic disorders. The aim of this project is to investigate the effect of stress on reality-monitoring, both on behavioral and neurophysiological aspects


Clinical Trial Description

Forty healthy subjects will be included in the study. Participants will be subject to a standardized stress protocol, half of them receiving an active stress and the other half receiving a placebo. All participants will also complete a reality-monitoring task, electrophysiological (EEG) recordings as well as socio-demographic and psychometric evaluations ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05595434
Study type Interventional
Source Hôpital le Vinatier
Contact SARTLET Lydie
Phone 0437915531
Email lydie.sartelet@ch-le-vinatier.fr
Status Not yet recruiting
Phase N/A
Start date April 30, 2024
Completion date November 16, 2025

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