Healthy Participants Clinical Trial
Official title:
Evaluation of the Safety and Pharmacokinetics of a Single Dose of Linzagolix in Female Subjects With Normal and Impaired Renal Function
The primary objective of this study is to assess the pharmacokinetics (PK) of linzagolix in subjects with varying degrees of impaired renal function compared to matched control subjects with normal renal function
This is a Phase 1, non-randomized, open label, single-dose study to evaluate the effect of
varying degrees of impaired renal function (i.e., mild, moderate, severe Renal Impairment
(RI), and End-Stage Renal Disease (ESRD) on hemodialysis) on the PK, safety, and tolerability
of linzagolix and its major metabolite, KP017.
Up to 40 adult female participants will be enrolled.
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