Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers

Healthy Participants Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00943696
• Other study ID #: Fonduestudie_EKGs
• Status: Completed
• Phase: Phase 4
• First received: July 20, 2009
• Last updated: June 24, 2010
• Start date: August 2009
• Est. completion date: October 2009

Study information

• Verified date: June 2010
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: UZurich
• Study type: Interventional

Clinical Trial Summary

Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been subjected to controlled study

A classic example is the Swiss cheese fondue. The intake of white wine, tea and cherry schnapps (Kirsch) are often attributed either positive or negative effects on the gastrointestinal tract.

In this study the effect of white wine vs. tea intake during and an alcoholic digestive following a high fat, high calorie Swiss fondue meal on gastric emptying and visceral perception will be investigated using a randomized, controlled study design.

The fondue will be labeled with non-radioactive 13C octanoate for assessment of gastric emptying by breath-test.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: October 2009
• Est. primary completion date: October 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 19 Years to 60 Years

Eligibility

Inclusion criteria: • able to communicate well with the investigators and provide written consent

• Body Mass Index: 19-30 kg/m2

Exclusion criteria: • physical co-morbidity requiring active treatment

• psychiatric (DSM IV) disorders limiting the ability to comply with study

• use of medications influencing upper GI motility

• evidence of current drug or alcohol abuse

• history of gastrointestinal disease or surgery except appendicectomy or hernia repair

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

• Healthy Participants

Intervention

Dietary Supplement:
• Ingestion of white wine vs. tea during and an alco
4 x 50ml glasses of white wine (12% alcohol) or tea will be taken according to a randomization scheme After the meal 1 x 20ml of Kirsch (40% alcohol) or tea will be taken

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
University of Zurich	COOP

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Effect of white wine vs. tea on gastric emptying		4 hours	No