Healthy Male Clinical Trial
Acebrophylline is metabolized by being separated into Ambroxol and 7-theophylline when
orally administered as a salt composed of an acid-base as a compound that was synthesized by
and chloride (salifying) the ambroxol to 7-theophylline. Acebrophylline is selectively
applied to the bronchial or lung tissue and inhibit the activity of phospholipase
bronchoalveolar shows the expectorant action to raise the surface activity of the alveolar,
leukotrienes (LTs) and by suppressing the production of prostaglandins (PGs), showed potent
anti-inflammatory activity, bronchial was celebrated by reducing the bronchial
hyperreactivity to normal state is allowed to recuperate or extended.
It was developed to improve compliance improve pharmaceutically Surfolase
capsule(Acebrophylline 100mg) that intake twice daily 100mg to Surfolase CR(Acebrophylline
200mg) that intake once daily 200mg
n/a
Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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