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Healthy Male Subjects clinical trials

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NCT ID: NCT05425407 Completed - Exercise Clinical Trials

Effects of Collagen Peptide Supplementation on Muscle and Tendon Damage and Function

Start date: April 12, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to investigate the acute and short-term effects of collagen peptides (Collagen Peptan) on muscle and connective tissue during an eccentric overload training period. Currently, all studies investigating the effects of post-exercise collagen supplementation did this in the absence of whey proteins, which are part of the standard recommendations for post-exercise recovery. The investigators will therefore investigate whether the combined intake of whey proteins and collagen peptides ensures a better recovery of exercise performance and whether it can prevent or reduce symptoms of muscle and tendon overload during a three-week eccentric overload training period (n = 22).

NCT ID: NCT05369858 Completed - Clinical trials for Healthy Male Subjects

A Mass Balance and Biotransformation Study of [14C]SKLB1028 in Chinese Healthy Male Subjects

Start date: August 6, 2021
Phase: Phase 1
Study type: Interventional

This is a single-centre, open-label, mass balance and biotransformation study in healthy male subjects utilising a single oral dose of [14C] SKLB1028.

NCT ID: NCT05337267 Completed - Clinical trials for Healthy Male Subjects

Phase I Study of Sintilimab in Healthy Chinese Male Subjects

Start date: April 13, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic similarity of sintilimab with different manufacturing process in healthy male subjects. Another purpose is to determine safety, and immunogenicity of sintilimab with different manufacturing process,also to determine Pharmacodynamics of sintilimab with different manufacturing process in 12 healthy male subjects.

NCT ID: NCT05275010 Completed - Clinical trials for Healthy Male Subjects

A Study in Healthy Male Subjects to Investigate the Comparability of Pharmacokinetics of the Fixed-Dose Combination of Pertuzumab and Trastuzumab Administered Subcutaneously Using a Handheld Syringe or Using the On-Body Delivery System

Start date: May 30, 2022
Phase: Phase 1
Study type: Interventional

This is a randomized, open-label, 2-arm, parallel-group, single-dose, multi-center study in healthy male subjects to investigate the comparability of the pharmacokinetics of the fixed-dose combination of pertuzumab and trastuzumab administered subcutaneously using the proprietary on-body delivery system or a handheld syringe with hypodermic needle.

NCT ID: NCT05245669 Recruiting - Clinical trials for Healthy Male Subjects

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Start date: February 7, 2022
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, three-arm, parallel-group, single-dose study to demonstrate bioequivalence of ENZ215 and EU- and US-sourced Prolia after a single 60-mg dose administered subcutaneously in healthy adult male volunteers.

NCT ID: NCT05126784 Completed - Clinical trials for Healthy Male Subjects

AVT03 With Prolia in Healthy Male Subjects

Start date: June 29, 2022
Phase: Phase 1
Study type: Interventional

This study has been designed as a randomized, double-blind, single-dose, parallel-group study in healthy adult male subjects 28 years to 55 years old. The study will assess the PK, PD, safety, tolerability and immunogenicity of AVT03 compared to Prolia when administered as a single SC dose.

NCT ID: NCT05072028 Completed - Clinical trials for Healthy Male Subjects

Mass Balance and Biotransformation Study of [14C]DBPR108 in Human

Start date: November 16, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center, open-label phase I clinical study to evaluate the mass balance and biotransformation pathways of [14C]DBPR108 in Chinese healthy adult male subjects, to reveal the overall pharmacokinetic characteristics of DBPR108 in human body, and to provide a reference for the rational administration.

NCT ID: NCT05005455 Completed - Clinical trials for Healthy Male Subjects

Study of Bevacizumab With Different Manufacturing Process in Healthy Male Subjects

Start date: July 30, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic similarity of bevacizumab with different manufacturing process in healthy male subjects. Another purpose is to determine safety, and immunogenicity of bevacizumab with different manufacturing process.

NCT ID: NCT04903158 Active, not recruiting - Clinical trials for Healthy Male Subjects

Relative Bioavailability Study of SHR3680

SHR-3680
Start date: January 6, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center, single-dose, randomized, open-label, parallel sstudy to evaluate the relative bioavailability of new and old formulations of SHR3680 tablets in healthy male subjects under fasting conditions.

NCT ID: NCT04850638 Completed - Clinical trials for Healthy Male Subjects

Drug Interaction Between SHR4640 Tablets and Furosemide Tablets in Healthy Volunteers (Single Center, Single Arm, Open, Self-control)

Start date: June 28, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study was to evaluate the effect of SHR4640 tablets on the pharmacokinetics of furosemide tablets in healthy male volunteers, using a single-center, single-arm, open, self-control design.