Drug Interaction With Metformin

Healthy Male and Female Subjects Clinical Trial

Official title: Pharmacokinetic Drug Interaction Study With Dapagliflozin and Metformin in Healthy Subjects

Status Completed

Clinical Trial Summary

The purpose of the study is to determine the effect of metformin on dapagliflozin exposure and the effect of dapagliflozin on metformin exposure in healthy volunteers. Additionally, the safety and tolerability of dapagliflozin will be assessed in the presence and absence of metformin in healthy volunteers

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Healthy Male and Female Subjects

• NCT number: NCT00546741
• Study type: Interventional
• Source: AstraZeneca
• Status: Completed
• Phase: Phase 1
• Start date: November 2007
• Completion date: February 2008