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NCT04724304 Clinical Trial

Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Healthy Adults Clinical Trial

Official title:
Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04724304
Other study ID # 20-000936
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 9, 2021
Est. completion date November 11, 2021

Study information
Verified date April 2022
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

Recruitment information / eligibility
Status Completed
Enrollment 115
Est. completion date November 11, 2021
Est. primary completion date November 11, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Age = 18 years. - Available for testing performed in Rochester, MN. - Willing to undergo both an echocardiogram with RTMPE and CMR. - Study subject providing consent. Exclusion Criteria: - Adults < 18 years. - BMI <30 kg/m^2. - Hypertension. - Diabetes Mellitus. - Stroke. - Cardiomyopathy or structural heart disease. - Known coronary artery disease or history of myocardial infarction. - Contraindication to echo enhancement agent or gadolinium administration such as an allergy. - Renal GFR < 50 mL/mL. - Females who are pregnant. - Subject unwilling to consent.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Real-Time Myocardial Echocardiography (RTMPE)
Uses sound waves (ultrasound) to produce an images of the heart. During RTMPE a microbubble contrast agent is administered through an intravenous line (IV) to make the images of your heart clearer.
• Magnetic resonance image (MRI)
Imaging that focuses on the heart or blood vessels to assess size and function of the heart's chambers, thickness and movement of the walls of the heart, and blood flow in the blood vessels.

Locations
Country Name City State
United States Mayo clinic Rochester Rochester Minnesota

Sponsors (1)
Lead Sponsor Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Myocardial blood volume Ratio in systole and diastole (MBVs/MBVd) by real-time myocardial perfusion echocardiography (RTMPE) Baseline
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