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Headache clinical trials

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NCT ID: NCT01591980 Withdrawn - Headache Clinical Trials

Effects of Perioperative Pregabalin for Post-Craniotomy Pain

Start date: August 2013
Phase: Phase 4
Study type: Interventional

Objective: To compare the incidence of chronic pain at 3 months among adults undergoing craniotomy between those received two different doses of pregabalin and those receiving placebo.

NCT ID: NCT01589588 Completed - Clinical trials for Cluster Headache Attacks

Administration of Oxygen to Cluster Headache Patients

Start date: April 2012
Phase: N/A
Study type: Interventional

This study will investigate the possible difference in treatment effect between three different oxygen delivery systems in the acute treatment of cluster headaches.

NCT ID: NCT01581281 Terminated - Migraine Clinical Trials

The Childhood and Adolescent Migraine Prevention Study

CHAMP
Start date: June 2012
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to test two medicines for migraine prevention in children and adolescents.

NCT ID: NCT01580280 Completed - Clinical trials for Cervicogenic Headache

Manual Therapy and Exercise in Patients With Cervicogenic Headache

Start date: April 2012
Phase: N/A
Study type: Interventional

Hypothesis: The group of cervicogenic headache patients receiving upper cervical and upper thoracic thrust manipulation will demonstrate significant and clinically important changes in outcomes when compared to the mobilization and exercise group.

NCT ID: NCT01552798 Terminated - Headache Clinical Trials

Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache

Tarot Headache
Start date: March 12, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to determine if a single, oral dose of a fast release aspirin 1000 mg provides relief compared to acetaminophen 1000 mg and placebo in subjects with tension-type headache pain.

NCT ID: NCT01550276 Completed - Clinical trials for Tension-type Headache

Treatment of Tension-type Headache With Articulatory and Suboccipital Soft Tissue Therapy

Start date: January 2010
Phase: N/A
Study type: Interventional

Background. Headache is one of the most common causes of consultation in primary health care and neurology in Europe. Cervical muscle tension can maintain a restriction of joint motion at the suboccipital level, facilitating the referred head pain. Objective. To evaluate the effectiveness of two manual therapy treatments for tension-type headache. Methods. A randomized double-blind clinical trial was conducted, for a period of 4 weeks and a follow-up at one month post-treatment. Eighty-four patients with tension-type headache were assigned to 4 groups (3 treatment groups and 1 control group). Treatments included manual therapy of suboccipital soft tissue inhibition, occiput-atlas-axis global manipulation, and a combination of both techniques. Outcome measures were: impact of headache, disability caused by headache, ranges of motion of the craniocervical junction, frequency and intensity of headache, and associated headache symptoms. Results. After 8 weeks, there were significant improvements in impact of headache (p=0.01), disability (p=0.001), and craniocervical flexion (p=0.03) for the suboccipital soft tissue inhibition group; in headache impact and disability (p=0.000), pain intensity (p=0.02) and craniocervical flexion (p=0.004) and extension (p=0.04) for the occiput-atlas-axis group; and in impact (p=0.002), functional disability (p=0.000), headache frequency (p=0.002) and intensity (p=0.001), craniocervical flexion (p=0.008) and extension (p=0.003) and associated headache symptoms (p=0.01) for the combined therapy group, with effect sizes from medium to large. Conclusions. Occiput-atlas-axis and combined therapy group treatments are more effective than suboccipital soft tissue inhibition for tension-type headache. The treatment with suboccipital soft tissue inhibition, despite producing less significant results, also has positive effects on different aspects of headache.

NCT ID: NCT01545466 Completed - Migraine Clinical Trials

Non-drug Interventions for Migraines

Start date: February 2012
Phase: N/A
Study type: Interventional

This proposal describes a randomized controlled pilot trial investigating feasibility, safety, and migraine frequency in patients with migraines who undergo an 8 week mindfulness based stress reduction (MBSR) program compared to a wait-list control group.

NCT ID: NCT01540799 Completed - Clinical trials for High Frequency, High Disability Migraine

Pathway M-1: Sphenopalatine Ganglion Stimulation for the AcuteTreatment of High Disability Migraine Headache

Pathway M-1
Start date: February 2012
Phase: N/A
Study type: Interventional

The purpose of the clinical study is to evaluate the use of an implanted sphenopalatine ganglion (SPG) neurostimulator for the treatment of migraine headache pain, migraine headache symptoms and migraine frequency in high disability migraineurs.

NCT ID: NCT01530321 Completed - Clinical trials for Cervicogenic Headache

Cervicogenic Headache Dose-Response

CGH D-R
Start date: August 2012
Phase: Phase 1/Phase 2
Study type: Interventional

This study will determine the number of visits to a chiropractor for spinal manipulation and light massage necessary for the optimal relief of cervicogenic headache (headache with associated neck pain). Effectiveness of care will also be determined.

NCT ID: NCT01525303 Completed - Chronic Headaches Clinical Trials

Effects of Aerobic Exercise Within a Behavioral Treatment Program for Chronic Headaches

Start date: December 2011
Phase: N/A
Study type: Interventional

This proposed study seeks to examine whether adding an aerobic exercise prescription to a behavioral treatment program for chronic headaches will improve headache frequency and intensity, headache-related disability, and mood. It is hypothesized that participants who receive the exercise prescription at the start of treatment will show greater gains than those who receive the prescription halfway through treatment. It is also predicted that participants who begin the exercise component halfway through treatment will demonstrate greater improvement in the second half of treatment compared to the first half.