Clinical Trials Logo

Headache clinical trials

View clinical trials related to Headache.

Filter by:

NCT ID: NCT01851720 Terminated - Clinical trials for Headaches Associated With Subarachnoid Hemorrhage (SAH)

Randomized Trial for Pain Management in Low-grade Subarachnoid Hemorrhage

Start date: July 2012
Phase: Phase 2/Phase 3
Study type: Interventional

Headaches associated with subarachnoid hemorrhage (SAH) cause severe pain. Headache management is complex, requiring a balance between pain control and preservation of neurological assessment. Sufficient pain control can be achieved with narcotics, however, these carry numerous undesirable side effects. Most critically, all narcotics can result in respiratory depression and sedation. For patients who present without neurological defects but debilitating pain, management is particularly challenging. The sedative effect of narcotics confounds the management of these patients by interfering with the neurological examination. Pain management is also a significant concern for patient's families as they observe suffering without full understanding of the importance of preserved mental status. In order to control the pain associated with SAH headaches, the use of narcotics is often required despite the risks. This standard therapy involves an IV bolus dose delivered by the provider regularly as needed for pain control. A common approach to reduce pain in other patient populations, including acute pain relief following major spine surgery, is patient controlled analgesia (PCA). With the PCA method, patients deliver low doses of narcotics through a pain pump with preset maximal doses and frequency of delivery. We hypothesize that this approach to pain relief for SAH headaches will result in lower pain scores, greater patient and family satisfaction scores, and increased patient safety with lower narcotic doses minimally interfering with neurological assessment.

NCT ID: NCT01842763 Recruiting - Clinical trials for Refractory Chronic Headache Disorders

French Database of Occipital Nerves Stimulation in the Treatment of Refractory Chronic Headache Disorders

NGO
Start date: March 2013
Phase:
Study type: Observational

The purpose of this non interventional research is to set up a French database, initially for 3 years, of patients suffering from refractory chronic headache disorders (chronic migraine, cluster headache, chronic paroxysmal hemicranias, SUNCT syndrome, hemicrania continua, cervicogenic headache disorders), and treated by occipital nerves stimulation. Every team using this neuromodulation approach in France is likely to participate in the network. Fifty patients a year are expected. They will be informed about data which are collected and why they are collected. The data will come from medical files and questionnaires filling out by the patients. The data will be collected on a case report form adapted to each refractory chronic headache disorder. The case report form pages will be faxed to the coordinating team who will enter the data in the database and analyse the data in a descriptive manner. These data are social and demographic data, medical data (headache features, headache functional and emotional impact, medications, and concomitant medical conditions), technical data (kind of electrodes and implantable pulse generator used, stimulation parameters chosen), and safety data. This research should provide an update on practices, an evaluation of the efficacy and long term safety of occipital nerves stimulation, and perhaps help in identifying response predictive factors to this neuromodulation approach.

NCT ID: NCT01828684 Completed - Migraine Disorders Clinical Trials

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With Migraine

Start date: March 2013
Phase: N/A
Study type: Interventional

Approximately 9% of men and 18% of women suffer from migraine headaches. Almost all migraine sufferers report light sensitivity during a headache. Some people with migraine report that light can trigger their migraines and some people with migraine are light sensitive all of the time. The investigators have recently determined that certain colors of light are more likely to trigger migraines than other colors. In this study the investigators want to know if people who wear glasses that block these colors of light will have fewer migraine headaches.

NCT ID: NCT01821807 Completed - Clinical trials for Complications; Anesthesia, Spinal and Epidural, in Pregnancy

Comparison of Two Spinal Needles Regarding Postdural Puncture Headache

Start date: June 2013
Phase: N/A
Study type: Observational

The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1. 26 Gauge Quincke (cutting-tip needle) 2. 26 Gauge Atraucan (atraumatic needle) The investigators will observe: 1. Number of spinal punctures 2. Time required for the spinal anesthesia procedure Patients will be evaluated after 7 days for: 1. Headache 2. Backache

NCT ID: NCT01808664 Completed - Low Back Pain Clinical Trials

Promoting Patient-Centered Counseling to Reduce Inappropriate Diagnostic Tests

Start date: April 2013
Phase: N/A
Study type: Interventional

In this study, the investigators will develop and evaluate a novel intervention using standardized patients (SPs) -- or actors playing the roles of patients -- to enhance physicians' patient-centered counseling skills regarding two frequently overused, potentially inappropriate services in primary care: magnetic resonance imaging (MRI) for acute low back pain and bone densitometry in women at low-risk for osteoporosis. The investigators will further evaluate whether intervention effects on physician patient-centeredness generalize to counseling regarding other costly, unnecessary diagnostic tests.

NCT ID: NCT01806155 Recruiting - Headache Clinical Trials

Prevalence of Post-craniotomy Headache in Siriraj Hospital

Start date: March 2013
Phase: N/A
Study type: Observational

Headache after major craniotomy may be a problem in taking care of the patients. The investigators want to identify the incidence of headache after major craniotomy and also the risk factors.

NCT ID: NCT01792817 Completed - Cluster Headache Clinical Trials

Non-invasive Neurostimulation of the Vagus Nerve for the Treatment of Cluster Headache

CH
Start date: February 2013
Phase: N/A
Study type: Interventional

Multi-center, prospective, double-blind, randomized, sham-controlled pivotal study of non-invasive vagus nerve stimulation with the GammaCore® device for the acute treatment of cluster headache. The study compares the safety and effectiveness of an active treatment (GammaCore) against a sham treatment.

NCT ID: NCT01791400 Completed - Migraine Disorders Clinical Trials

Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache

Start date: July 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine which drug makes lower migraine headache

NCT ID: NCT01790074 Completed - Clinical trials for Cervicogenic Headache

Trigger Point Therapy in Cervicogenic Headache

Start date: October 2010
Phase: N/A
Study type: Interventional

It is a pilot randomized controlled trial comparing real and simulated manual treatment of trigger points (TrPs) in patients with cervicogenic headache (CeH). The purpose of the current randomized clinical pilot trial was to determine the preliminary effects of TrP manual therapy in individuals with CeH with sternocleidomastoid muscle active TrPs as compared to manual contact over the muscle tissues.

NCT ID: NCT01785459 Terminated - Benign Headache Clinical Trials

Bupivacaine for Benign Headache in the ED

Start date: October 2013
Phase: Phase 2
Study type: Interventional

Headache is a common chief complaint of patients presenting to the emergency department (ED), accounting for approximately 3 million ED visits per year. Headache treatment is often a source of frustration for both patients and providers. By the time patients with benign headaches arrive in the emergency department, they have often failed non-invasive therapeutic attempts and providers are often left with few therapeutic options. Treatment of benign headache varies between providers, often including systemic medications with a multitude of possible side effects. In recent years, there has been preliminary investigation into anesthetic injections for the undifferentiated headache patient presenting to the emergency department. It has been proposed that these patients presenting with benign headache might benefit from this novel treatment. Patients that present to the Emergency Department with a diagnosis of benign or primary headache with serious or life-threatening causes of headache will be offered enrollment into the study. Following consent, subjects will receive either 0.5% bupivacaine injected bilaterally in the paraspinal musculature of the cervical spine or the standard treatment with intravenous Prochlorperazine. The subjects will complete a validated pain scale before, and 20 minutes after injection. At twenty minutes post-injection, the subject will be reevaluated for symptoms. The subject will then be eligible for discharge or standard treatment at the discretion of the treating physician. Subjects will be followed for 72 hours after enrollment for headache recurrence. Subjects will be monitored for immediate and post-discharge complications.